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2 Acta of Bioengineering and Biomechanics

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Laboratory tests for strength paramaters of brain aneurysms

Toth B. K., Nasztanovics F., Bojtar I.

Acta of Bioengineering and Biomechanics

2007

Vol. 9, nr 2

3-7

The presentation is focused on the analysis of biophysical properties of cerebral aneurysms, diagnosed and delineated in living human individuals. An aneurysm is a bulging out of a part of the wall of a blood vessel. The aim of our research was to delineate flow patterns inside the aneurysm and its parent artery, to estimate stresses at critical points of the aneurysm wall, to model the haemodynamic effect of different surgical and endovascular tools in order to define the optimal one in a particular case, and to estimate the likelihood of a later aneurysm rupture. For this reason we carried out a lot of different laboratory tests to analyse the mechanical parameters of the aneurysm wall. We made a comparative study of some material models reported in the literature to describe the mechanical response of arteries. These are models for incompressible materials. For this reason we perform uniaxial and biaxial measurements to have appropriate parameters for the models of underlying material.

Analysis of the mechanical parameters of human brain aneurysm

Brigitta K. T., Raffai G., Bojtar I.

Acta of Bioengineering and Biomechanics

2005

Vol. 7, nr 1

3-22

Cardiovascular disease is one of the most frequent reasons of mortality in the western word. Nowadays the mechanical properties of biological soft tissues were treated from a continuum mechanical perspective. The aim of this article is to investigate the mechanical response of arterial tissue. We present some three-dimensional finite element model to study the mechanical effects. The arterial wall is composed mainly of an isotropic matrix materiał (elastin) and collagen fibers from two families which are arranged in symmetncal spirals. These fibers induce the anisotropy in the materiał response. So the constitutive law of an artery is orthotropic. We want to develop a new constitutive law for arterial wall mechanics. In addition we make a comparative study of some material model used in the literature to describe the mechanical response of arteries. These are the following models: 1. Linearly elastic model. 2. Neo-Hookean model for incompressible materials. 3. Mooney-Rivlin model for incompressible materials. For this reason we make uniaxial and biaxial measurements to have appropriate parameters for the underlying material models. We investigate the biomechanical properties of strips from human cerebral aneurysms from surgery and cadavers. (An aneurysm is a bulge along a blood vessel.) Meridional and circumferential. thick and thin parts were distinguished respectively. This paper focuses on the analysis of the haemodynamic pattern and biophysical properties of cerebral aneurysms. diagnosed aiid delineated in living human individuals. The aim of this research is to estimate stresses at critical points of the aneurysm wall and its parent artery, and to estimate the likelihood of a later aneurysm rupture.