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Development of a standard phantom for diffusion-weighted magnetic resonance imaging quality control studies: A review

Manson Eric Naab, Mumuni Abdul Nashirudeen, Shirazu Issahaku, Hasford Francis, Inkoom Stephen, Sosu Edem, Aikins Mark Pokoo, Mohammed Gedel Ahmed

Polish Journal of Medical Physics and Engineering

2022

Vol. 28, Iss. 4

169--179

Various materials and compounds have been used in the design of diffusion-weighted magnetic resonance imaging (DWMRI) phantoms to mimic biological tissue properties, including diffusion. This review thus provides an overview of the preparations of the various DW-MRI phantoms available in relation to the limitations and strengths of materials/solutions used to fill them. The narrative review conducted from relevant databases shows that synthesizing all relevant compounds from individual liquids, gels, and solutions based on their identified strengths could contribute to the development of a novel multifunctional DW-MRI phantom. The proposed multifunctional material at varied concentrations, when filled into a multi-compartment Perspex container of cylindrical or spherical geometry, could serve as a standard DW-MRI phantom. The standard multifunctional phantom could potentially provide DW-MRI quality control test parameters in one study session.

Diffusion of lead ions trough the Poznan Clay (Neogene) and through glacial clay

Mieszkowski R.

Geological Quarterly

2003

Vol. 47, No 1

111-118

Two main kinds of migration through clays can be distinguished: advection and diffusion. The main force for advective flow is the water pressure gradient, while ionic concentration gradients drive diffusion. In compacted clays the hydraulic permeability is very low, therefore the diffusion process predominates. Clays can be considered as waste repositories. This paper shows characteristics of the diffusion process and the application of this process to modelling of waste migration in clays. Additionally, a new calculation method for the apparent diffusion coefficient using the finite-difference method is given. Experimental, values of the apparent diffusion coefficient Dapp for Poznan Clay and glacial clay are respectively 2.2_2.6 _ 10-12 m2/s and 2.6_4.4 _ 10-12 m2/s.