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New Ionic Liquids with Organic Anions

Pernak J., Goc I.

Polish Journal of Chemistry

2003

Vol. 77 / nr 8

975-984

A series of 1-alkylimidazole and 1-alkoxymethylimidazole has been converted to the ionic form. The resulting salicylates and lactates constitute a new category of ionic liquids. They are air and water stable. Some physical properties of these salts were measured, including melting point, boiling point, density and their solubility in some common organic solvents and in water. For 1-alkyl- and 1-alkoxymethylimidazolium lactates values of minimal inhibitory concentration (MIC) and of minimum biocidal concentration (MBC) were determined. Effects of lactate structure on microbiological activity were defined. In aqueous solution the obtained lactates reacted with ozone, unlike their commercially available analogs.

Rate and Equilibrium in Aqueous 1:2 Chelation of Copper(II) by 2-Pyridinecarboxylic Acid Hydrazide. Antituberculosis Activity

Hernando J., Blanco C. A., Caballero I., Prieto T.

Polish Journal of Chemistry

2002

Vol. 76 / nr 12

1673-1680

Chelation reactions of 2-pyridinecarboxylic acid hydrazide, widely used drug in antituberculous regimens, with copper(II) have been investigated in aqueous solution at a temperature of 25_C. The ionization equilibria of the ligand and the stability of the metal-ligand complexes have also been characterized. Kinetic results show that the rate constant for monochelated complex formation is several times larger than the rate constant for dichelated complex formation. Adetailed mechanism is proposed to account for the kinetic data.