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EN
Purpose: The science that involves nano-sized particles have been shown to have a huge impact on a variety of research fields, such as electronics, medicine, engineering, robotics and technology. The involvement of biological agents in nanoscience helped in the origin of bionanotechnology, which is deeply rooted in therapeutic and medical applications. This review provides an initiative to understand the combination of biological molecules and nanoparticles in delivering a great impression in the world of therapeutics. Design/methodology/approach: Conjugation of nanoparticles with the biological molecules makes them more friendly for the living system by increasing biocompatibility and reducing toxicity. Findings: Growing research in this area has revealed the identification and characterization of numerous biological agents of nano-sized that can serve as better carrier systems. They are exploited in the development of advanced nanoparticle-based targeted drug delivery systems. In general, either the combined form or the one in the derived form of nanoparticles from different biological organisms provides a valuable understanding of their specifications and importance in different therapeutic aspects. Research limitations/implications: The combined form of biological molecules and nanoparticles is not yet well understood, and this might provide a baseline for prospects. Originality/value: This review provides an understanding of biologically synthesized and conjugated nanoparticles and their potential as therapeutic norms and highlights their applications, especially in the clinical field.
EN
Antimicrobial and antifungal polymers are gaining the attention of pharmaceutical makers and industrial design. Nanospheres-Polymers attached Platinum(II) / (IV) complexes have been synthesized to investigate antimicrobial activities. Firstly, nanospheres involving Schiff bases were synthesized from (aminomethyl) polystyrene and four substitute salicylaldehyde (2-hydroxy benzaldehyde, 5-fluoro-2-hydroxy benzaldehyde, 5-kloro-2-hydroxy benzaldehyde, 5-bromo-2-hydroxy benzaldehyde). Secondly, polymers attached Platinum(II) / (IV) complexes have been prepared by means of template method. The IR spectra show that the ligands act in a monovalent bidentate fashion all nanospheres involving Schiff bases. Square-planar and octahedral structures are proposed for Pt(II) and Pt(IV), respectively. All these substances have been examined for antibacterial activity against pathogenic strains, and antifungal activity. In particular, Pt(IV) complexes were more potent bactericides than all of the synthesized substances.
PL
Nanoczastki srebra wykazują silne właściwości bakteriobójcze, grzybobójcze oraz wirusobójcze. Ze względu na swoje właściwości znajdują szerokie zastosowanie w wielu produktach codziennego użytku, m.in. medycznych, kosmetycznych, tekstylnych czy gospodarstwa domowego. Srebro w postaci nanocząstek może być uwalniane do środowiska na każdym etapie cyklu życia produktów, a jego głównym nośnikiem są ścieki. Proces migracji powoduje, że na toksyczne działanie nanosrebra jest narażona większość organizmów wodnych środowiska.
EN
Silver nanoparticles have the strong bactericidal, fungicidal and virucidal properties. Because of its properties they are widely used in many of daily life products, for example medical, cosmetic, textile and household. Silver in the form of nanoparticles can be released into the environment at each stage of the life cycle of products, and their main carrier is wastewater. The migration process causes that on the toxic effect of nanosilver most organisms of the aquatic environment are exposed.
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