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EN
Psoralen and angelicin are organic, natural chemical compounds, belonging to the furanocoumarin group, which are quite common in nature. Among others, these compounds are present in plants of the celery, rutaceae, mulberry and bean families, such as celery, carrot, lemon and fig. Interestingly, they exhibit a variety of biological activities, for instance insecticidal, anticonvulsant, anticancer, and antioxidant properties. For this reason, they are commonly used in different area of life. For example, psoralen is used in photochemotherapy as a photosensitizer in the treatment of psoriasis or acquired vitiligo (PUVA therapy). However, there is evidence that overexposure to psoralen and angelicin can also cause adverse effects. For these reasons, a number of analytical methods have been developed for their determination in environmental samples, while the vast majority of them are based on separation techniques. This paper discusses issues related to psoralen and angelicin and their analytics.
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