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Content available remote Effect of the oxidation on the tribological behaviour of steels
EN
The work presented in this study focus on the application of the method of the plans of experiences (MPE) to the study and the optimization of the quantification of the wear of the steels (XC48, A60) under the effect of a factor of environment in the occurrence Hydrogen. Modeling can draw inspiration from the mathematical models established by the (MPE) in order to analyze more deeply the phenomenon of the wear while taking account of the various relevant factors [1]. The MPE, introduced is a consistent set of tools and methods algèbro-statistics to establish and analyze the relationships in the quantities studied (responses) and their sources of variations (factors) [2]. This analysis may be qualitative: study of “screening" (determination of influential factors) or quantitative: methodology of the surfaces of answers (variation of responses according to the influential factors). In all cases, it has for the purpose of determination of mathematical models approached the answers expressed in terms of the factors. These models are deducted from the values obtained of series of experiments. The definition of these plans of experiences determines the measurable quality of models. The multiple facets of the MPE are then used as the basis for the development of strategy to optimize [3].
EN
This article reviews the recent advances in acetylcholinesterase (AChE) biosensors as screening devices for the detection of samples contaminated wich neurotoxic compounds, with a focus on those dcveloped for carbamate insecticides. The use of AChE enzymes from different organisms or genetically modified to improve the limits of detection and extend the range of detectable compounds is also reviewed. Finally, the auto-recovery of the AChE activity after inactivation and the research performed on multi-analyte detection are discussed. AChE inhibition-based biosensors are probably the key tools for performing fart and reliable screening of samples suspected to contain hazardous insecticides. These devices are designed to respond to increasing needs for environmental protection and food safety.
PL
Przedstawiono przegląd literaturowy związany z tematyką wykorzystania bioczujników zawierających acetylocholinoesterazę (AChE), jako narzędzi w analityce przesiewowej próbek zawierających związki neurotoksyczne (w szczególności insektycydów karbaminianowych). Bioczujniki wykorzystujące inhibitory AChE mogą się prawdopodobnie stać kluczowymi narzędziami w analityce przesiewowej próbek, podejrzewanych o zanieczyszczenie insektycydami. Na co istnieje rosnące zapotrzebowanie w zakresie ochrony środowiska i bezpieczeństwa żywności.
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