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Human osteoblast-like cells MG 63 in cultures on polymer-carbon-alginate composites

Grausova L., Bacakova L., Stodolak E., Blazewicz S., Mikołajczyk S.

Inżynieria Biomateriałów

2005

R. 8, nr 47-53

6--9

Adhesion and growth of human osteoblast-like MG 63 cells (seeding density of 17964 cells/cm2) was studied in cultures on the following 7 groups of artificial materials developed for bone tissue engineering: terpolymer of polypropylene, polytetrafluorethylene and polyvinyldlfluoride (CPO), terpolymer reinforced wlth carbon fibres (CP4) or carbon fabric (CP5), terpolymer reinforced with carbon fibres and with pores created by addition and dissolution of alginate fibres (CP6) or powder (CP7), terpolymer reinforced with carbon fibres and containing the alginate powder (CP8) or fibres (CP9). On day 1 and 3 after seeding, the numbers of MG63 cells on all tested materials was similar to the values obtained on the control polystyrene culture dish (PS). However, on day 7, the cell number, ranging from 17766±3180 to 67002±6850 cells/cm2, increased in the following order: CP0