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Pulse Nebulization in Pneumatic Devices

Gradoń L., Sosnowski T. R., Podolec Z.

International Journal of Occupational Safety and Ergonomics

1999

Vol. 5, No. 1

31--42

Aerosols of a physiological salt solution and aqueous solutions of salbutamol, sodium cromoglicate, and dornase aifa were generated in a pneumatic nebulizer and analyzed in a system with controlled humidity of air as a carrier gas. Mass distribution of aerosol particles and yield of generation for pulse nebulization were measured. Pulsation of generation was realized with an attachment maintained by a computer program. Opening times of the valve were in the range 50-800 ms. The results indicate the possibility of improving aerosol particle delivery to the lung using a pulse generation system.