Santolinol, a new lignan has been isolated from the chloroform soluble fraction of Salvia santolinifolia and as signed the structure 1 on the basis of spectral studies including 2D NMR. In addition three bifuranolignans namely didemethylpinoresinol 2, (+) fraxiresinol 3 and (+) 1-hydroxysyringaresinol 4 have also been isolated for the first time from this species. All these compounds showed potent inhibitory potential against the enzyme lipoxygenase.
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