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3 International Letters of Chemistry, Physics and Astronomy

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Synthesis of some New Quinoxalines Bearing Pyridinyl Thiazole Moiety

Kathrotiya H. G., Naliapara Y. T.

International Letters of Chemistry, Physics and Astronomy

2015

Vol. 52

74--83

Keeping the objective to build up a new structural class of quinoxaline, a new series of quinoxaline derivatives bearing the pyridinyl thiazole nucleus have been synthesized by base-catalyzed chloro-amine condensation reaction approach. The protocol offers expeditious and easy synthesis with excellent yield. The chemical structures of the synthesized compounds were elucidated by 1H NMR, 13C NMR, FT-IR, elemental analysis, and mass spectral data.

Synthesis and Antimicrobial Activity of [2"-aryl(quinoxaline)-3-yl]-(methylene phenyl amino)-6-[bis-(2"'-chloro ethyl) amino]-4-Methoxy-1,3,5-Triazine

Kathiriya P. J., Purohit H. D., Purohit D. M.

International Letters of Chemistry, Physics and Astronomy

2015

Vol. 49

130--136

The compounds 5d, 5e, 5g, 5i showed moderate antimicrobial activity then other synthesized compounds, compare with known standard drugs.

Structure parameter correlation of some quinoxaline derivatives through IR and 13C NMR spectra

Thirunarayanan G., Muthuvel I., Sathiyendiran V.

International Letters of Chemistry, Physics and Astronomy

2014

Vol. 19, iss. 2

198--207

A series of 6-substituted quanoxaline derivatives have been synthesized and examined their purities by literature method. The infrared and 13>/Sup>C NMR spectral data of these quinoxalines were correlated with Hammett substituent constants, F and R parameters using single and multi-regression analysis. From the results of statistical analysis, the effect of substituents on the spectral frequencies has been studied.