Basidiomecetes Phlebia radiata and Panus tigrinus have been suggested as good producers of yellow laccase. Some cultural and environmental factors influencing the enzymatic activity in shaken flasks and aerated fermenter cultures were evaluated to improve the process yield. Application of some cultural conditions as well as the use of a solid-state tube hioreactor made it possible to obtain 7989 nkat/1 laccase from Panus tigrinus and 3032 nkat/1 laccase from Phlebia radiata in six days.
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