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Aryl Chalcones as Efficient Precursors for Deriving Oxazine: Solvent-free Synthesis and Antimicrobial Activities of some Oxazine-2-amines

Thirunarayanan G., Sundararajan R., Arulkumaran R.

International Letters of Chemistry, Physics and Astronomy

2014

Vol. 4

82--97

A series of some oxazine derivatives has been synthesised by fly-ash:H2SO4 catalyzed solvent-free cyclization of aryl chalcones and urea under microwave irradiation. The yields of the oxazines were more than 85 %. The synthesised oxazines were characterized by their physical constants, analytical and spectroscopic data. The antimicrobial activities of these oxazines have been studied using Bauer-Kirby method.