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1 Prace Naukowe Politechniki Warszawskiej. Elektronika

1 2008

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Molecular NOR logic gate

Wąsiewicz P., Wójtowicz-Krawiec A., Płucienniczak A.

Prace Naukowe Politechniki Warszawskiej. Elektronika

2008

z. 165

237-244

Molecular computing created for implementing logic systems, solving NP-difficult problems on nanoscale depends on DNA self-assembly abilities and on modifying DNA with the help of enzymes during genetic operations. In the typical DNA computing a sequence of operations executed on DNA molecules in parallel is called an algorithm, which is also determined by a model of DNA chains. This methodology is similar to the soft hardware specialized architecture driven here by heating, cooling and enzymes, especially polymerases used for copying strings. This work presents a unique approach to implementation of OR, NOR logic gates on molecules. It requires the representation of signals by DNA molecules. The presented method allows for constructing logic gates with many inputs and for executing them at the same quantity of elementary operations, regardless of a number of input signals. The NOR gate was implemented with the help of modified polymerase Taq, which stops its activity, when it meets a molecular obstacle on its way. The appropriate experiment was conducted to confirm the possibilities of the suggested implementation. Laboratory results were discussed.