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1 Wiadomości Chemiczne

1 2023

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Właściwości fizykochemiczne, biologiczne i aplikacyjne izocyjanków. Część 2, Zastosowanie w medycynie i materiałoznawstwie

Pawlak Marta, Pobłocki Kacper, Drzeżdżon Joanna, Jacewicz Dagmara

Wiadomości Chemiczne

2023

[Z] 77, 3-4

239--256

Isocyanides are compounds with a triple bond between a nitrogen atom and a carbon atom. Thanks to this structure, there is an electron lone pair on the carbon atom, which allows these compounds to participate in many reactions in organic chemistry. Due to their properties and the number of reactions in which they can participate, this group has been applied in medicine. Both natural and synthetic isocyanides have antifungal, antibacterial, antimalarial, antiviral and anticancer properties. The reactions involving them allow for a much simpler and faster synthesis of many pharmaceuticals. In addition, these compounds have application properties, making it possible to obtain polymers. Despite the polymerization of these compounds raising many objections, many polymeric materials based on isocyanides have found applications both in science and in everyday life.