The aim of this study was to develop a convenient method for superimposing SPECT images and EEG maps. This work was performed as part of research concerning feasibility of improving the localization of epileptic foci comparing to the standard SPECT examination by applying the technique of EEG mapping. The described method relies on making five EEG electrodes visible in SPECT images, calculating the coordinates of these electrodes in SPECT image space, approximating the coordinates of the remaining electrodes used in EEG recording and then computing a sequence of 3D EEG maps spanning on all the electrodes. An example of visualization of EEG and SPECT data integration was presented. The maximum error of the five base electrodes location was assessed below 10 mm. Assuming the exact placement of the base electrodes the accuracy of the proposed method was estimated below 5.5 mm.
The aim of the study was analysis of histograms of selected sequences of EEG maps to assess variability of isopotential areas. In clinical practice this variability is evaluated using visual inspection that is subjective and may be difficult in revealing of subtle differences. Variability of isopotential areas is manifested by changes of isopotential areas as well as changes of their topolocalisation. The histograms of total map areas include the information concerning the ispotential area variability, while histogram analysis of particular areas of map may be useful for evaluation of variability of isopotential areas configuration. Basing on the examples containing the period before, during and after generalized seizure activity, the variability of constellations of isopotential areas in EEG maps and related to that diversity of their histogram types were presented. The work includes examples of series of EEG map histograms with their statistical analysis and the description of method used for the quantitative assessment of the histogram series variability for the maps sequences containing seizure activity.
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