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2 International Letters of Chemistry, Physics and Astronomy

2 2015

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Spectral and Microbial Studies of some Newly Synthesized Schiff Base Derivatives of 2-(1H-benzo[d]oxazole-2-ylthio)-N-(4-acetylphenyl)acetamide

Maru J.J., Patel G. R., Yadav R.

International Letters of Chemistry, Physics and Astronomy

2015

Vol. 44

57--65

The author has synthesized novel biological active compounds by condensation of N-(4-Acetyl-phenyl)-2-(benzooxazol-2-ylsulfanyl)-acetamide with defferent substituted of acid hydrazide in the presence of catalytic amount of acetic acid. A series of benzoxazole having azomethine group were confirmed by various spectroscopic techniques. The new compounds were examined for antibacterial effects again different strain of bacteria and antifungal were high to lowest Minimum Inhibition Concentration (MIC) values.

Antimicrobial Screening of Synthesized some Novel Azomethines via Organic Base

Patel G.R., Maru J.J., Yadav R.

International Letters of Chemistry, Physics and Astronomy

2015

Vol. 43

25--33

The author has synthesized azomethines in which carbonyl group is replaced by amine of acid hydrazides. The intermediates were prepared by using 2-mercapto benzimidazole with N-(4-Acetyl-phenyl)-2-chloro-acetamide in the presence of K2CO3. The Resulted product was further treated with different substituted of acid hydrazide in ethanol to yield the titled compounds using a catalytic amount of acetic acid. New products were examined for their antibacterial effects against Gram-positive and Gram-negative strains and antifungal were highly potent with lowest MIC Values. The structural assignments of the new products were done on the basis of FT-IR, NMR, Mass spectroscopy and elemental analysis.