Wyniki wyszukiwania - BazTech

Ograniczanie wyników

1 Acta Chromatographica

1 2010

Znaleziono wyników: 1

Liczba wyników na stronie

Wyniki wyszukiwania

Wyszukiwano:
w słowach kluczowych: Adhatoda vasica

Sortuj według:

Ogranicz wyniki do:

Simultaneous RP-HPLC quantification of vasicine and vasicinone in Adhatoda vasica and its formulation

Suthar A, Hamarapurkar P, Patil P, Phale M, Katkar K, Mundada G, Chauhan V. S

Acta Chromatographica

2010

Vol. 22, no. 4

599--608

A simple, specific, and precise RP-HPLC method with photodiode-array detection has been developed for simultaneous analysis of the quinazoline alkaloids vasicine and vasicinone, pharmacologically important constituents of Adhatoda vasica . The compounds were separated by use of 0.1% trifluoroacetic acid in water:acetonitrile 90:10 as isocratic mobile phase at a flow rate of 1.0 mL min -1 Under these conditions, plots of integrated peak area against concentration were linear over the ranges 0.05–10.0 μg mL -1 and 0.5–100.0 μg mL -1 ( r 2 = 0.999 and 0.998) for vasicine and vasicinone, respectively. Mean recovery was 99.06% for vasicine and 98.69% for vasicinone. The method is therefore suitable for routine analysis of vasicine and vasicinone in Adhatoda vasica plants of different varieties and in herbal medicinal products prepared from the plants.