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1 International Letters of Chemistry, Physics and Astronomy

1 2015

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Synthesis and Antimicrobial Activity of (1-acetyl/1-phenyl)-3-{4'-[(4'''-chlorophenyl) (phenyl) methyl amino] phenyl}-5-Aryl-Pyrazoline

Guna J. V., Bhadani V. N., Purohit H. D., Purohit D. M.

International Letters of Chemistry, Physics and Astronomy

2015

Vol. 49

104--108

1-Acetyl-3-{4'-[(4'''-chlorophenyl) (phenyl) methyl amino] phenyl}-5-aryl-pyrazolines (3a-3l) and 1-Phenyl-3-{4'-[(4'''-chlorophenyl) (phenyl) methyl amino] phenyl}-5-aryl-pyrazolines (4a-4l) have been synthesized. The products have been assayed for their biological activity against Gram +ve, Gram -ve bacteria and fungi. Some of the compounds showed moderate activity in concentration 50 μg/ml. The structure of the products have been elucidated by IR, 1H-NMR, mass spectral data elemental analysis and Thin layer chromatography.