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2 International Letters of Chemistry, Physics and Astronomy

2 2013

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Scavenging activity, anti-inflammatory and diabetes related enzyme inhibition properties of leaves extract from some varieties of Phoenyx dactylifera l.

Eddine L. S., Segn L., Noureddine G., Mohammed Redha O., Mokni Sonia

International Letters of Chemistry, Physics and Astronomy

2013

Vol. 9, iss. 2

125-135

In this study we investigate the antioxidant, anti-inflammatory, and antidiabetic activities of ethanolic leaves extracts of three selected varieties of Phoenyx dactylifera L. namely: “Ghars”, “Deglet Nour” and “Hamraya”. The assessment of the antioxidant potential of crude leaves extracts, using superoxide anions inhibition, DPPH and total antioxidant activity essays, was carried out. Furthermore, the anti-inflammatory properties of the extracts were determined by measuring the inhibition of nitric oxide (NO) production. Moreover, the antidiabetic effect was evaluated by inhibition of α-amylase enzymes. The total phenolic content measured by Folin-ciocalteu method was as well conducted. The raw leaves extracts of the selected varieties was found to contain a high content of total phenolic content (342.45 mg GAE/gDW for GE) and therefore exhibited a higher antioxidant activity and inhibitory effect of radicals scavenging activity against DPPH and superoxide anion (IC50 = 7.44 μg/mL and 39.11 μg/mL respectively). The three varieties exhibited significant inhibition nitric oxide using in-vitro assay (IC50 = 240.28 μg/mL for GE). The extracts also displayed high inhibition actions against α-amylase enzymes. The results suggest that the leaves of the three selected varieties of Phoenyx dactylifera can be considered as a good source of natural antioxidant and anti-inflammation drugs as well as potent antidiabetic medicine.

A comparative study of the antioxidant activity and phytochemical composition of leaves extract between three varieties of date palm tree

Eddine L. S., Ladjel S., Mohamed O. M.

International Letters of Chemistry, Physics and Astronomy

2013

Vol. 9, iss. 2

162-171

The date palm (Phoenyx dactylifera) consisted, for the people of southern Algeria, as tree of providence. Dates and their extracts are also used for many centuries as a medicine against allergy, inflammation, constipation and gastro-protective; they also have a high antibacterial and antioxidant activity. However, no studies are conducted to evaluate the extract from the leaves of date palm (Phoenyx dactylifera) in point of view of phytochemical composition, antimicrobial and the antioxidant activity. In this study, we have determined the phenolic compounds, antioxidant and antimicrobial activity of methanolic extracts from three varieties of leaves tree. According to the results the leaves extracts have very important values for polyphenols (215.24 to 156.46 mg GAE / g DW) and high antioxidant activity (324. 45 to 206.21 mg GAE / g DW), Diphenyl-1 picrylhydrazyl radical-scavenging activity (IC50 = 2.98 to 4.83 μg / ml); also the three extracts reveal a considerable antimicrobial potency and antifungal considerable activity, the diameter of inhibition is 35.2 to 39.5 mm (concentration 50 mg/ml) for Candida albicans ATCC 90026.