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Development of Hydrophobic Surgical Forceps using Powder Injection Molding and Surface Treatment

Park D. Y., Park B. R., Gal C. W., Lin D., Han J. S., Jeong M.-S., Bollina R., Hwang W., Park S. J.

Archives of Metallurgy and Materials

2018

Vol. 63, iss. 1

473--480

Hydrophobic surgical forceps of end-effectors for laparoscopic operations or minimally invasive surgery were developed through powder injection molding (PIM) and surface treatment. Processing conditions for mixing, debinding, and sintering were investigated to produce defect-free components. An optimum solid loading was determined by torque rheometry experiments. The optimized processing conditions for debinding and sintering were designed through the measurement of weight loss and shrinkage behavior by thermogravimetric analysis and dilatometry experiments. After producing the surgical forceps based on the optimized processing conditions via PIM, surface treatment was carried out to generate the hydrophobic structure on the surface.

Performance of classification methods in a microarray setting: a simulation study

Van Sanden S., Lin D., Burzykowski T.

Biocybernetics and Biomedical Engineering

2007

Vol. 27, no. 3

15-28

Dudoit et al., Lee et al., and Statnikov et al. investigated the performance of several classification methods applied to real-life microarray data. Due to the availability of only a few datasets, only a limited number of settings could be evaluated. Also, the true classification and the set of truly differentially expressed genes were unknown. In order to overcome these limitations, a simulation study was conducted, by using a linear mixed effects model to simulate microarray data under different scenarios. Several classification methods were compared with respect to their ability to discriminate between two classes of biological samples in various experimental settings.