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EN
The paper discusses the flow of an incompressible non-Newtonian fluid due to stretching of a plane elastic surface in a saturated porous medium in the approximation of boundary layer theory. An exact analytical solution of non-linear MHD momentum equation governing the self-similar flow is given. The skin friction co-efficient decreases with an increase in the visco-elastic parameter k1 and increase in the values of both the magnetic parameter and permeability parameter.
EN
Purpose: Lubricants prepared with metal oxide nanoparticle additives are found to have better tribological properties. In this work the widely used commercial SN lubricating oil is added with SiO2 nanoparticle and the tribological characteristics are studied. Wear tests were conducted on plain oil and oil with nanosized silica (SiO2) additives using a four ball tribo-tester. Design/methodology/approach: The wear images of the ball specimens were analyzed using confocal microscope to measure the topography of the wear parameters such as wear scar diameter, depth of wear, angle of the wear. Findings: It is found that the gear oil with silica nanoparticles is found to have improved properties. Results show a considerable reduction in the values of wear scar diameter, wear angle and wear depth for the gear oil added with SiO2 nanoparticles of 0.4 wt. %. Originality/value: In the work carried out, a new innovative technological approach to analyze the tribological properties of lubricating oil by finding the wear scar diameter, wear angle and wear depth is reported.
EN
An isocratic RP-HPLC method has been developed and validated for simultaneous analysis of ambroxol hydrochloride (AMB) with cetirizine hydrochloride (CTZ) and of ambroxol hydrochloride (AMB) with levo -cetirizine dihydrochloride (LCTZ) in combined solid dosage forms. Formulations containing AMB with CTZ (tablets) and AMB with LCTZ (capsules) are used as antihistaminic H 1 blockers. Chromatography was performed on a 250 mm × 4.6 mm, 5-µm particle size, C 18 (ODS) column with a 45:30:30 ( v/v ) mixture of 30 mM aqueous ammonium sulphate (pH 5.5), acetonitrile, and methanol as mobile phase at a flow rate of 1 mL min -1 . The detection wavelength was 230 nm and analysis was performed at room temperature. Hydrochlorothiazide was used as internal standard for both formulations. Plots of drug-to-internal standard peakarea ratios (response factor) against respective concentrations were linear in the range 3 to 20 µg mL -1 for AMB and in the range 1 to 11 µg mL -1 for CTZ and LCTZ. The method was precise (RSD < 2) and accurate for analysis of both drugs in pharmaceutical dosage forms. Statistical data and results from recovery studies were reported for both formulations.
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