Wyniki wyszukiwania - BazTech

Ograniczanie wyników

3 Engineering of Biomaterials

Powiadomienia systemowe

Sesja wygasła!
Sesja wygasła!

Znaleziono wyników: 3

Liczba wyników na stronie

Wyniki wyszukiwania

Sortuj według:

Ogranicz wyniki do:

Antibacterial fabrics modified with betulin for medical and general applications

Sowiński Artur D., Tarachowicz Ludwik A., Kłeczek Anna, Brzezińska Natalia, Pyza Maciej, Gabor Jadwiga, Gierek Zuzanna, Zabrowarny Adam, Swinarew Andrzej S.

Engineering of Biomaterials

2023

vol. 26, no. 169

23--26

This study examines the potential use of betulin as an alternative to silver in enhancing vinyl-coated fabrics. Silver, commonly used to impart antimicrobial properties to polymers, raises environmental and cytotoxicity concerns. Betulin, known for its antibacterial, anti-inflammatory, antiviral, and antifungal characteristics, emerges as an eco-friendly alternative. The study highlights the possible applications of betulin in various sectors, such as medical, military, and public settings, where addressing the challenge of harmful biofilms is critical. The aim of this research was to assess the possible effectiveness of betulin as a modifier in polyvinyl chloride (PVC) coated textiles. The study involved extracting betulin, preparing plasticizer-based betulin premix, incorporating it into plastisol, and then coating fabrics to analyze its effect on surface bioactivity. Preliminary tribological studies were conducted to assess the durability of the coating. According to the ISO 22196:2007 standard, significant antibacterial effects were observed, with an activity rating (R) ranging between 1.55 and 2.0. In addition, tribological studies indicated an improvement in coating durability compared to conventional PVC coatings. The results suggest that betulin shows potential as a cost-efficient and environmentally friendly alternative, contributing to improved product functionality while minimizing environmental impact. Further research is planned to investigate the potential of betulin in polymer modification and to exploit its positive impact on human health and environmental sustainability.

Polylactide-based composite materials for 3D printing and medical applications - the effect of basalt and silicon dioxide addition

Pyza Maciej, Brzezińska Natalia, Kulińska Karolina, Gabor Jadwiga, Barylski Adrian, Aniołek Krzysztof, Garczyk-Mundała Żaneta, Adebesin Kayode, Swinarew Andrzej

Engineering of Biomaterials

2022

vol. 25, no. 166

29--39

Polymers are compounds that play a key role in the development of many fields of science, including emergency medicine. Currently, there are increasing requirements for biomedical polymers in terms of producing lighter and more ecological equipment. To meet these requirements, a composite material was developed: polylactide (PLA) with the addition of modifiers - basalt and silicon dioxide (SiO2). PLA was chosen as a biodegradable polymer that naturally decomposes in the environment. This is very important, regarding a large number of single-use materials made of microplastics polluting the environment. The samples were made by additive 3D printing and then immersed in swimming pool water, chlorine solution, and distilled water. FTIR analysis showed the influence of the environment on the intensity and shift of PLA absorption bands. Microscopic analysis provided information on surface morphology, roughness, and potential defects. Tribological and micromechanical tests showed that the additions of basalt and silica to the PLA material influenced the morphological structure and the average area of the wear trace, volumetric wear, and average coefficient of friction. In the presence of chlorine solution, distilled water, and pool water under real conditions, the SiO2 addition made the PLA material more resistant to abrasion, as compared to the basalt addition. However, additives did not significantly affect the PLA material hardness, and the samples with basalt turned out to be more resistant to deformation.

Fabrication of filter membrane of organic compound to protect the upper respiratory tract from viral and bacterial infections, including SARS-CoV-2, compliant with FFP2 standard

Brzezińska Natalia, Pyza Maciej, Kłeczek Anna, Kulińska Karolina, Gabor Jadwiga, Garczyk-Mundała Żaneta, Świnarew Andrzej

Engineering of Biomaterials

2022

vol. 25, no. 166

2--11

Bacteria, viruses, and other pathogens in the surrounding environment are biological threat to human health and life. The development of various diseases in the world, as well as the pandemic caused by the rapid spread of the SARS-CoV-2 virus, have increased the demand for the use of upper respiratory protection devices. Out of concern for the natural environment, the aim of this work was to develop an innovative solution i.e. the FFP3 filtering membrane made of an organic compound. First, preliminary tests of the FFP2 mask were carried out to assess the chemical composition, morphological structure - fibers geometry, thickness, density, and arrangement. The FTIR analysis study was conducted to confirm that the main chemical in the mask was polypropylene (PP) and high-density polyethylene (HDPE). Optical, confocal microscopy and computer microtomography studies showed the fibers structure. They were densely arranged and their thickness was less than 1 den. The fiber structure of the FFP2 mask was also compared before and after immersing in betulin, an organic compound obtained from birch bark via the Soxhlet extraction. In addition, the assessment of microbiological activity was made on the reference strain Escherichia coli ATCC 25922, and the anti-inflammatory activity on normal human skin fibroblasts on polycarbonate with betulin. The studies showed that betulin supported the material antibacterial and anti-inflammatory properties.