Wyniki wyszukiwania - BazTech

Ograniczanie wyników

2 Polish Journal of Chemistry

Znaleziono wyników: 2

Liczba wyników na stronie

Wyniki wyszukiwania

Sortuj według:

Ogranicz wyniki do:

Synthesis, Characterization, Spectroscopic and Antimicrobial Activity studies of Pyrimidine Dithiocarbamate Macrocyclic Complexes

Nishat N., Rahis-ud-din, Haq M.

Polish Journal of Chemistry

2004

Vol. 78 / nr 5

645-652

The ligands disodium salts of thiobarbituric acid (Na2L1) and 5,5-diethylbarbituric acid (Na2L2) and their transition metal complexes of the type [M2(L1)2] and [M2(L2)2], where M= Mn(II), Co(II), Ni(II), Cu(II), Zn(II), have been synthesized. The transition metal(II) complexes have been characterized by a range of techniques including IR, 1H NMR,UV-visible spectroscopy, magnetic moment measurements, elemental analyses and molar conductance measurements. The spectroscopic studies indicate, that the reaction of L1and L2 with a divalent metal ions form binuclear dithiocarbamate macrocyclic complexes. The molar conductivity measurements suggest, that all of the complexes are non-electrolytes. The magnetic moment values and electronic spectra reveal that the Ni(II) and Cu(II) complexes are square-planar, while Mn(II), Co(II) and Zn(II) complexes are tetrahedral. All of the compounds have been screened for antimicrobial activity against Staphylococcus aureus (gram-positive bacteria) and Escherichia coli (gram-negative bacteria). The results show that all the compounds inhibit the growth of bacteria. All the complexes showed better activity as compared with the ligands.

Synthesis and Characterization of Complexes of Transition Metal Ions with New Pentaazamacrocyclic Ligands

Nishat N., Rahis-ud-din, Haq M. M.

Polish Journal of Chemistry

2003

Vol. 77 / nr 12

1731-1740

New multidentate ligands 1,4,7,9,12-pentaaza-10,11-dioxo-8,9,12,13-bis-(1_,3_-dioxo- 6,6-diethyl-2_-hydropyrimidine)-trideca-7,13-diene, (L1) and 1,4,7,9,13-pentaaza-10,12- dioxo-8,9,13,14-bis-(1_,3_-dioxo-6,6-diethyl-2_-hydropyrimidine)-tetradeca-7,14-diene (L2) have been prepared by the reaction of 5,5-diethylbarbituric acid, diethylenetriamine, diethyl oxalate and 5,5-diethylbarbituric acid, diethylenetriamine, diethyl malonate. Their coordination properties with the first row of transition metal ions have been explored. The macrocyclic complexes were characterized by elemental analysis, IR, 1H NMR, UV-visible spectroscopy, magnetic moment measurements and molar conductance measurements. The electronic spectra and magnetic moment measurements are discussed with respect to assignment of square planar and tetrahedral structure except chromium(III), iron(III) ions. The chromium(III) and iron(III) complexes are considered to be octahedral. Molar conductance measurements suggest that the complexes of divalent metal ions are 1:1 electrolytes, while the trivalent metal ions are nonelectrolytes. The compounds have been tested against gram-positive bacteria Staphylococcus aureus and gram-negative bacteria Escherichia coli. The results show that all the compounds inhibit the growth of bacteria.