In its initial presentation, the P system formalism describes the topology of the membranes as a set of nested regions. In this paper, we present an algebraic structure developped in combinatorial topology that can be used to describe finer adjacency relationships between membranes. Using an appropriate abstract setting, this technical device enables us to reformulate also the computation within a membrane and proposes a unified view on several computational mechanisms initially inspired by biological processes. These theoretical tools are instantiated in MGS, an experimental programming language handling various types of membrane structures in a homogeneous and uniform syntax.
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