Carbon fiber-reinforced carbon (CFRC) composites were modified by grinding with abrasive papers, laser irradiation, coating with diamond-like carbon (DLC), creation of pores by laser perforation and various combinations of these treatments, and seeded with human osteoblast-like MG 63 cells. Twenty four hours after seeding, the lowest cell numbers were obtained on the non-ground, non-coated composites with Type 1 laser perforations (diameter 0.1 mm, depth 0.2 mm, spacing 0.3 mm), i.e., on samples with relatively high surface roughness (R a = 17.7 ± 0.9 μm, S = 93.0 ± 2.0 μm). On the other hand, the cells on these samples were well-spread, adhering with a relatively large cell-material projected area. In comparison with these samples, a significantly higher number of cells were obtained on composites treated with a DLC coating, especially those with laser perforation 2 (diameter 0.4 mm, depth 0.8 mm, spacing 1.2 mm). The cells on both types of laser-perforated samples started to colonize pores created by the laser beam.
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