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1

Effect of curcumin and pirfenidone on toxicokinetics of paraquat in rat by UPLC–MS/MS

Wang S., Lin Z., Su K., Zhang J., Zhang L., Gao Z., Ma J., Wang X.

Acta Chromatographica

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2018

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Vol. 30, no. 1

26--30

EN

The rats were randomly divided into paraquat group, curcumin treatment group, and pirfenidone treatment group. The concentration of paraquat in rat plasma was determined by an ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method over the range of 10–2000 ng mL−1. Chromatographic separation was achieved on a BEH HILIC (2.1 mm × 100 mm, 1.7 μm) column. The mobile phase was consisted of acetonitrile and 10 mm ammonium formate buffer (containing 0.1% formic acid) with gradient elution pumped at a flow rate of 0.4 mL min−1. Protein precipitation with acetonitrile was used as sample preparation. Compared with the paraquat group, there is statistical toxicokinetic difference for curcumin treatment group and pirfenidone treatment group, AUC(0 − t) decreased (P < 0.05), clearance (CL) increased (P < 0.05) for curcumin or pirfenidone treatment group, and Cmax decreased (P < 0.05) for curcumin treatment group. The results showed that treatment by curcumin and pirfenidone could relieve acute paraquat poisoning in rats.

2

Effect of activated carbon on methomyl poisoning by urine metabolomics base on gas chromatography–mass spectrometry

Li L., Hu L., Chen B., Dong Y., Lin Z., Wang Z., Wen C., Wang X., Wang S.

Acta Chromatographica

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2018

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Vol. 30, no. 1

21--25

EN

In this study, we developed a urine metabolomic method by gas chromatography–mass spectrometry (GC–MS) combination with biomedical results to evaluate the effect of activated carbon on methomyl poisoning rats. The rats were divided into four groups, methomyl group, two activated carbon treatment group, and control group. According to the biochemical results, it indicated that activated carbon treated rats could cause liver and kidney function changes. According to the urine metabolomics results, activated carbon treatment group (10 min) and activated carbon treatment group (30 min) could be distinguished from methomyl group, and activated carbon treatment group (10 min) could be separated from activated carbon treatment group (30 min) rats, which indicated that the treatment of rats by activated carbon in different time had a different effect. The results indicate that metabolomic method by GC–MS may be useful to elucidate activated carbon treated on methomyl poisoning rats.

3

Development and validation of UPLC–MS/MS method for determination of eupatilin in rat plasma and its application in a pharmacokinetics study

Geng P., Luo X., Peng X., Lin Z., Chen W., Zhang J., Wen C., Hu L., Hu S.

Acta Chromatographica

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2018

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Vol. 30, no. 4

231--235

EN

Eupatilin, mainly derived from Artemisia asiatica (Asteraceae), is an O-methylated flavone with various bioactivities. In the present study, a validated ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method was established for the quantification of eupatilin in rat plasma with the internal standard (IS) of tussilagone and the protein precipitation of plasma samples was performed using acetonitrile–methanol (9:1, v/v). The eupatilin and IS were eluted separately on a UPLC BEH C18 column (2.1 mm × 100 mm, 1.7 μm) with the gradient mobile phase consisted of 0.1% formic acid and acetonitrile. The protonated analytes were quantified by multiple reactions monitoring (MRM) mode with an electrospray ionization (ESI) source operated in positive ion mode. The calibration plots were found to be linear over the range from 2 to 1000 ng/mL for eupatilin in rat plasma. Both of the intra-day and inter-day precision variations (RSDs) were ≤13%. The recoveries of eupatilin in rat plasma were between 83.7% and 94.6%, and the accuracy of the method ranged from 95.8% to 107.6%. In addition, the validated method was applied to pharmacokinetic study of eupatilin after an intravenous dose of 2 mg/kg to rats.

4

Fluid mechanics analysis and realization of electric and program for solar chimney power generation project—a case in China

Zhiqi L., Liqun L., Zhiyi S., Jinbao L., Chunxia L., Lin Z.

Przegląd Elektrotechniczny

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2012

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R. 88, nr 10a

224-228

EN

Utilization of solar chimney power generation project has proved to be a promising approach for future applications. This paper gives the fluid mechanics analysis and electric and program realize for a solar chimney power generation project located in Taiyuan. Three groups geometric parameters of project is assumed such as chimney diameter, outer limit height of collector, and tilted angle of collector, and the output characteristics at different parameters is discussed to gain the optimal designed structure. Then the overall structure of system is designed to achieve the real-time data acquisition and system control. Finally, the control software and test hardware is designed based on the proposed overall structure of system, and the experimental and simulation results prove the correctness and effectiveness of designed solar chimney power generation system.

PL

W artykule analizuje się mechanikę przepływu strumienia ciepła z systemie elektrowni słonecznej z kominem solarnym. Układ analizuje się na przykładzie takich elektrowni usytuowanych w prowincji Taiyan w Chinach. Przedstawiono projekt elektrowni, badania właściwości oraz oprogramowanie. (Analiza mechaniki strumienia ciepła w projekcie elektrowni słonecznych z kominem solarnym na przykładzie systemu zrealizowanego w Chinach)

5

Szybki wzrost kryształów jako metoda postępowania z odpadowym Mg(OH)2

Liu W., Huang F., Lin Z.

Chemik

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2012

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Vol. 66, nr 9

919-928

PL

Istnieje duże zapotrzebowanie na badania nad detoksykacją nanoodpadów i recyklingiem zużytych nanosorbentów. W niniejszym artykule dokonano przeglądu badań prowadzonych w tej dziedzinie przez naszą grupę. Przetwarzanie nano-Mg(OH)2 z ładunkiem Cr(VI) stanowi nową strategię zagospodarowania nanoodpadów. Nanoodpady zostały przetworzone w nietoksyczny materiał masowy i stężony roztwór zawierający Cr(VI) na drodze szybkiego wzrostu nanokryształów, który spowodował desorpcję i całkowite oddzielenie Cr(VI) od substancji stałej. Stężony roztwór Cr(VI) można poddać recyklingowi przemysłowemu, a oczyszczony produkt stały można stosować w produkcji materiałów ceramicznych, powłok do metali i ognioodpornych tworzyw sztucznych. Przedstawiono też strategię recyklingu nanosorbentu Mg(OH)2 do stosowania go do usuwania Cr(VI) z roztworów o małym stężeniu Cr(VI).

EN

There is a strong demand for the investigations on the detoxification of the nano-wastes or recycling of the loaded nanoadsorbents. This article reviews the studies of our group in this field. The treatment of Cr(VI) loaded nano-Mg(OH)2 introduces a new strategy for nano-waste disposal. The nano-wastes were converted into a nontoxic bulk material and a concentrated solution containing Cr(VI) by the rapid growth of nano-cystals which leads to the desorption and complete separation of Cr(VI) from the solid. The concentrated Cr(VI) solution can be recycled in the industry and the detoxified solid product can be reutilized in ceramics, metal coatings or flame-retardant plastics. Finally, a recycling strategy of Mg(OH)2 nano-adsorbent was provided for the enrichment of Cr(VI) from aqueous solutions of low-concentration Cr(VI).

6

3D Measurement and Modelling of Magnetic Properties of Soft Magnetic Composite

Zhu J., Lin Z., Guo Y., Huang Y.

Przegląd Elektrotechniczny

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2009

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R. 85, nr 1

11-15

EN

The soft magnetic composite (SMC) is a new type of soft magnetic material made of insulated iron powders. Its special characteristics could enable the development of low cost high performance electrical machines. This paper presents the measurement and modelling of magnetic properties of SMC under 3D magnetizations. Detailed descriptions of the 3D magnetic property tester, principle of measurement, core loss models, and experimental results are included and discussed.

PL

Magnetycznie miękkie kompozyty (soft magnetic composites – SMC) są nowym rodzajem magnetycznie miękkich materiałów wykonanych z elektrycznie izolowanych cząsteczek proszku żelaza. Specjalne charakterystyki takich materiałów mogą umożliwić rozwój tanich i wydajnych maszyn elektrycznych. Artykuł prezentuje pomiary i modelowanie własności magnetycznych SMC w warunkach przemagnesowania 3D. Podano dokładny opis użytej techniki pomiarowej, modelu i wyników pomiarowych.

7

LMI Approach to Stability Analysis of Three-dimensional Systems

Galkowski K., Lin Z., Xu S., Lam J.

Bulletin of the Polish Academy of Sciences. Technical Sciences

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2003

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Vol. 51, nr 4

361-379

EN

An LMI approach to investigating the stability and related problems for linear three-dimensional discrete systems is described. The stability and lower bounds for stability margins are discussed for all principal three-dimensional state-space models. The particular emphasis is put on the robust stability for the uncertain case. A numerical example is presented to illustrate the results developed in the paper.

8

A novel recognition method for color objects different illuminations

Wang J., Lin Z., Zhu J.

Machine Graphics and Vision

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2001

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Vol. 10, No. 1

103-112

EN

Color images depend on the scene illumination, but these image colors are not stable features for object recognition. We develop an algorithm that transforms color into its normal form such that is invariant to different illuminations. Since the normalization process is to make color image compact, solors distorted in different ways from the same object due to illumination change will all be compacted to their most compact feom and become similar. After compaction process, the histograms for the same objects under different illuminations are very similar. The recognition can be performed by simple matching method. A set of experiments on complex scenes under various other reported techniques for color normalization.