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EN
Molecular computing created for implementing logic systems, solving NP-difficult problems on nanoscale depends on DNA self-assembly abilities and on modifying DNA with the help of enzymes during genetic operations. In the typical DNA computing a sequence of operations executed on DNA molecules in parallel is called an algorithm, which is also determined by a model of DNA chains. This methodology is similar to the soft hardware specialized architecture driven here by heating, cooling and enzymes, especially polymerases used for copying strings. This work presents a unique approach to implementation of OR, NOR logic gates on molecules. It requires the representation of signals by DNA molecules. The presented method allows for constructing logic gates with many inputs and for executing them at the same quantity of elementary operations, regardless of a number of input signals. The NOR gate was implemented with the help of modified polymerase Taq, which stops its activity, when it meets a molecular obstacle on its way. The appropriate experiment was conducted to confirm the possibilities of the suggested implementation. Laboratory results were discussed.
EN
This paper describes non-deterministic finite-state automaton based on DNA strands. The automaton uses massive parallel processing offered by molecular approach for computation and exhibits a number of advantages over traditional electronic implementations. This device is used to analyze DNA molecules, whether they are described by specified regular expression. Presented ideas are confirmed by experiment performed in genetic engineering laboratory.
EN
Implementation of the inference system based on DNA chains molecular computing is a new paradigm to perform calculations using nanotechnology means. This work presents a new approach to the implementation of inference engines based on DNA. It introduces the subject of inference methods designed to be used with molecular expert systems. The main part of this work includes the concept of the inference engine based on a rule tree specially customized to allow implementation using deoxyribonucleic acid chains. The approach presented allows the drawing of inferences based on a variable number of predicates using the most reliable techniques employed in standard operations of genetic engineering. In this approach cross cells are bases of multidimensional DNA structures. An experiment was conducted to confirm the capabilities of the implementation suggested. In addition, laboratory evaluation results and perspectives for the further use of the proposed architectural approach are discussed.
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