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Structural investigations of nifuroxazide, p-hydroxy-N'-(5-nitrofurfurylidene)benzhydrazide

Pniewska B., Januchowski M.

Polish Journal of Chemistry

1998

Vol. 72, nr 12

2629-2634

The crystal and molecular structure of the antibacterial compound nifuroxazide was carried out by X-ray diffraction methods. The crystals belong to the triclinic system, space group P1. The lattice parameters are: a=6.879(6) A, b=8.164(5) A, c=11.410(7) A, alpha=78.87(5) degree, beta=78.91(5) degree, gamma=69.68(7) degree. The molecule is essentially planar except of the phenyl ring somewhat twisted with respect to the residual part of the molecule. In the crystal structure, the molecules are hydrogen bonded, forming infinite planar sheets.