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Synthesis and antimicrobial screening of some new pyrimido[1,2-a]benzimidazole derivatives

Shah N. M., Joshi H. S.

International Letters of Chemistry, Physics and Astronomy

2014

Vol. 6

56--60

Some new pyrimido[1,2-a]benzimidazole derivatives were synthesized by reacting 2-amino benzimidazole and chalcones in n-butanol at reflux temperature. In our present study we have used various heterocyclic chalcones derived from furfural and substituted acetophenones. All synthesized compounds were characterized by IR, 1H NMR and Mass spectroscopy. All synthesized compounds were screened for their antimicrobial activity against gram positive and gram negative bacteria which showed moderate to good activity.