DNA strand replacement technology has the advantages of simple operation which makes it becomes a common method of DNA computing. A four bit binary number Complementer based on two-domain DNA strand displacement is proposed in this paper. It implements the function of converting binary code into complement code. Simulation experiment based on Visual DSD software is carried out. The simulation results show the correctness and feasibility of the logic model of the Complementer, and it makes useful exploration for further expanding the application of molecular logic circuit.
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