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EN
In this work, effects of various parameters, including regularity of sewing, distance of holes from the edge of the tissue (D), distance between holes (L), suturing pattern, and material and size of the suture on the leakage of human large intestine anastomosis site were investigated, using finite element method (FEM). The effects of various parameters of suturing on leakage were investigated in four different steps: 1. regularity of suturing; 2. variations in D (small, medium and large), and L (small, medium and large); 3. suturing pattern; and 4. material and size of the suture. The models mimicked two sides of human large intestine tissue, sewn together. By considering a 50 mm displacement on right-side free edge of tissue, the surface areas of the gaps created around the holes were calculated, and a gap surface area equals to, or greater than 0.07 mm2 was considered as the leaking specimen. Results showed that in the case of irregular suturing, compared to the regular one, the likelihood of leakage increases. Additionally, in the cases with large D and medium L, the likelihood of leakage decreases. It was found that zigzag pattern has less leakage probability compared with simple continuous and interrupted patterns. Furthermore, by increasing the diameter and elastic modulus of the suture, the likelihood of leakage will increase. Results of this study are in agreement with experimental evidences.
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