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Bionic design of tube formation in the integrated cellular structure

Tanishita K., Ueda A., Sudo R., Ikeda M., Mitaka T.

Biocybernetics and Biomedical Engineering

2007

Vol. 27, no. 1-2

83-87

The individual cells in the reconstructed cellular structures do not necessarily receive sufficient oxygen and necessary substances supply only by diffusion, and it is necessary to install a blood vessel network formation in the cellular structure. In other words, the vessel network formation is essentially required to achieve cellular function, and to develop a technology of reconstruction of the vessel network installed in the three-dimensional cellular architecture is needed. Here the procedure of the tube formation of blood vessels and bile canaliculi (BC) in vitro is focused on, demonstrating a possibility of tube formation in cellular structures reconstructed in vitro. Particularly, attention to the role of biomechanical processes in the tube formation was paid.

First principles molecular dynamics simulations for amorphous HfO2 and Hf1-xSixO2 systems

Ikeda M., Kresse G., Nabatame T., Toriumi A.

Materials Science Poland

2005

Vol. 23, No. 2

401--406

Amorphous phases of HfO2 and Hf1-xSixO2 were obtained using the Projector Augmented Plane Wave method through the melt and quench technique. For the pure HfO2 system, several pore channels appear in the structures. Changes to x in the Hf1-xSixO2 were also studied. As the concentration of Si increases, the size of the pore channels increases, much space appears and two- fold oxygen atoms increase. By calculating the heat of formation energy, it was found that phase separation between amorphous HfO2 and SiO2 occurs at x> 0.1.