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PL
Komitet Chemii Analitycznej PAN jest jednym z 12 komitetów naukowych PAN. Powołany został w 1975 roku, jednak swoją historię datuje już od 1955 roku, kiedy to utworzono Komisję Analityczną przy Komitecie Nauk Chemicznych Polskiej Akademii Nauk.
EN
The sample preparation stage is a critical step in the whole analytical procedure as it often determines the efficiency of the process. What is particularly noticeable in the area of biological samples. Blood, milk, urine, saliva or tissue are only few examples of complicated biological matrix, that require a optimization of sample pre-treatment method for particular analytes. For these purpose, the aim of following chapter was to characterized main problems with sample preparation method as well as highlighted some innovative ways how to improve sample preparation stage. Attention was particularly focused on the use of dispersive solid phase extraction (dSPE), which has achieved high growth in interest in recent years, mainly due to the simplicity and rapidity of performance. This method is not only used with commercially available sorbents, but also provides a basis for trying to apply new analytical tools for separation of analytes from matrix. Following the trends of nanotechnology and within the rules of green analytical chemistry, scientists are facing the challenges of determining and identifying compounds from various chemical groups. Frequently targeting analytes at trace concentration levels as well biological samples. In addition, attention is also focused on reagents reduction and shorter analysis time but also in terms of minimization of sample volume, which should to be collected. Herein the chapter presented describes exemplary new proposals in sorbents such as molecularly imprinted polymers (MIPs), supported ionic liquids (ILs), dendrimers and metal-organic framework (MOFs). In addition, it also looked at the potential use of magnetic nanoparticles as carriers. New sorbents in sample preparation together with modem instrumental techniques therefore allow the development of a procedure that will be characterized by high selectivity and specificity.
EN
The complexity of the structure of heparin anticoagulants requires appropriate sample preparation to be able to perform the analysis correctly. This stage of the analytical procedure is the most time-consuming and has a key impact on the obtained information. Therefore, it is important to improve the current and search for new solutions for the preparation of samples of anticoagulants as well as the separation and identification of components of such drugs. This paper discusses heparin drugs and new research directions and challenges related to the analytics of heparin anticoagulants.
PL
Artykuł na podstawie rozprawy doktorskiej pt.: 'Wpływ zanieczyszczeń środowiskowych na jakość mleka matki. Opracowanie innowacyjnych sorbentów i kropek kwantowych jako narzędzie analityczne w przygotowaniu próbek' nagrodzonej przez Komitet Chemii Analitycznej PAN w 2021 roku w konkursie na najlepsze prace doktorskie, nagroda ufundowana przez firmę Perlan Technologies.
PL
W oznaczaniu cytokin należy uwzględnić wiele czynników wpływających na ich zawartość, takich jak czas przechowywania próbki, pora, o jakiej pobrano próbkę, sposób karmienia czy silny stres matki karmiącej.
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