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EN
The automatic collision avoidance system introduced in this paper is a system constantly calculating optimal manoeuvring method from the risk and economic preference in the ship manoeuvring space where the course change and the deceleration are performed. The authors also propose a system that quantitatively evaluates the collision avoidance manoeuvring results. Based on the evaluation results of this system, the authors are setting parameters so that ship manoeuvring that does not give anxiety to target ships to be avoided is also realized in automatic collision avoidance manoeuvring. In addition, comparison between the manoeuvring results of the automatic collision avoidance system and the veteran captain's manoeuvring results was quantitatively compared by the proposed evaluation system. Verification experiments were successfully conducted to verify the effectiveness of the proposed automatic collision avoidance system on the actual ship navigating in congested waters.
EN
The necessity of verifying manoeuvring mathematical models in shallow water for studying the safety of ships using a ship-handling simulator is pointed out in this report. Several instances of verification of mathematical models in shallow water are introduced here based on measurements of motion conditions of full-scale ships and shallow water tank tests of models. Results of safety assessment tests of five manoeuvring phases are given using the verified manoeuvring mathematical models to discuss manoeuvring criteria in shallow water. Objective manoeuvring criteria for safety assessment in shallow water are proposed based on subjective judgement related to control margin assessed by more than 3,200 masters and pilots for over 325 simulation tests and by analysis of the study results of 15 full-scale ships.
EN
Novel Sugar Dendritic Gd-DTPA Complexes for MRI Contrast Agents were prepared and evaluated by in vitro and in vivo methods. The sugar dendritic MRI contrast agents have a good blood vesse pool character, and draw blood vessels and liver cancer remarkably clearer than the clinically using Gd-DTPA. Phospha sugar derivatives or phosphorus heterocyclic derivatives provided by functional groups such as epoxide, bromide, etc., were prepared and evaluated by MTT in vitro method. These phospha sugar derivatives showed excellent activities against leukemia cells as well as solid cancer cells in fashions of (i) higher activity, (ii) wider spectra, (iii) higher selectivity and specificity distingushing healthy and cancer cells, etc., compared with the molecular targeting chemotheraputic anti-cancer agent, Gleevec.
EN
Structural properties of various kinds of room-temperature synthesized C60 fullerene nanowhiskers were investigated by TEM and XRD. The C60 nanowhiskers prepared by use of toluene lost their initial solvated hexagonal structure faster than the C60 nanowhiskers prepared by use of m-xylene. The hexagonal structure of C60 nanowhiskers prepared by use of toluene was stabilized by adding C60[C(COOC2H5)2]. These results suggest that large solute molecules in the C60 nanowhisker matrix stabilize their initially solvated hexagonal structure. Furthermore, the addition of a sufficient amount of C60(2-methoxycarbonyl-N-methylpyrrolidine) into the m-xylene solution of C60 produced the C60 nanowhiskers indicating the formation of ordered solid solution of C60 and C60(2-methoxycarbonyl-N-methylpyrrolidine).
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