The authors have been developing various types of mock circulatory systems to evaluate a performance of artificial organs. Among several attempts, it was indicated that a simulation of the mitral valve region was very difficult due to a complicated shape and movement of the valve. In this paper, a new trial to install a porcine valve into the mock circulatory system is introduced. A fresh porcine valve with papillary muscles and chordae was fixed into the mitral position of the modified Windkessel-type mock circulatory system. To allow direct 3-D observation of the mitral annulus, a digital video camera and a laser displacement sensor were employed. A circulation was generated by a pneumatically-driven artificial ventricle. When a normal circulatory condition (pump rate: 70BPM, Flow: 3L/min) was selected, similar opening and closing motion to the natural mitral valve could be reproduced. Moreover, a diseased condition was made by shifting a position of papillary muscles. After this procedure, an abnormal movement, such as significant leakage, could also be reproduced.
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