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The effect of external wedge on the photoneutron dose equivalent at a high energy medical linac

Hashemi , S. M., Raisali G., Taheri M., Majdabadi A., Ghafoori M.

Nukleonika

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2011

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Vol. 56, No. 1

49-51

EN

Medical linacs used in radiotherapy produce bremsstrahlung spectra. In the energy range from 8 to 25 MV medical linacs produce, besides the clinically useful electron and photon beams, secondary neutrons. The aim of this study was to investigate the effect of an external wedge filter on the photoneutron dose equivalent produced by a medical linac at patient plane. Polycarbonate (PC) films were used for the determination of photoneutron dose equivalent produced by a Varian 2100 C/D linac working at 18 MV photon mode. Neutron dose equivalent was measured at distances 0, 10, 20 and 50 cm from the center of the X-ray beam for open field and after inserting a wedge filter. It was noted that by inserting the external wedge in the path of the X-ray beam, the photoneutron dose equivalent was increased compared to open field. It can be concluded that an external wedge, made from heavy materials may act like the other components of linac head, producing undesired photoneutrons and thus increasing patient dose.

2

Preparation and biological evaluation of [61Cu]bleomycin complex as a possible PET radiopharmaceutical in normal and fibrosarcoma-bearing animals

Jalilian A. R., Zandi H., Sardari D., Akhlaghi M., Kamali-Dehghan M., Shafaei K., Majdabadi A.

Nukleonika

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2009

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Vol. 54, No. 2

135-141

EN

[61Cu]bleomycin ([61Cu]BLM) was prepared using [61Cu]CuCl2 produced via natZn(p,x)61Cu. [61Cu]BLM was prepared under optimized conditions (room temperature, 45 min, 0.1 mg bleomycin for 92.5–370 MBq 61CuCl2) with radiochemical purity over 98% shown by HPLC and RTLC. [61Cu]BLM was administered into normal and tumor bearing rodents up to 210 min followed by biodistribution and co-incidence imaging studies. A significant tumor/non tumor accumulation was observed either by animal sacrification or an imaging method. [61Cu]BLM can be a potential PET radiotracer for tumor imaging.

3

Investigation on polycarbonate nanomembrane production based on alpha particles irradiation

Ziaie F., Shadman M., Yeganegi S., Mollaie A., Majdabadi A.

Nukleonika

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2009

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Vol. 54, No. 3

157-161

EN

Track-etched membranes were prepared in the Dosimetry Laboratory of Agricultural, Medical and Industrial Research School by exposing polycarbonate (PC) films with a thickness of about 20 μm to alpha particles emitted from 241Am followed by chemical etching in sodium hydroxide (NaOH) at different temperatures and solution concentrations. The PC films were prepared using the method of chemical solving, forming and drying in a vacuum oven. The etching rate of PC was related to the concentration of etching solution, etching temperature and time. Therefore, a series of track-etched membranes were produced using different etching parameters. The relation between the etching rate and the etching parameters were established from experimental data and can be used to control the average pore sizes of the PC track-etched membrane. The pore sizes and their structures were studied by an optical microscope (OM) and a scanning electron microscope (SEM) and the obtained results indicated that the pores across the PC films are cylindrically shaped.