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A pattern recognition approach to Emery-Dreifuss muscular dystrophy (EDMD) study

Sokołowska B., Jóźwik A., Niebroj-Dobosz I. M., Hausmanowa-Petrusewicz I.

Journal of Medical Informatics & Technologies

2014

Vol. 23

165--172

The algorithms of pattern recognition were used for differentiation between two forms of Emery-Dreifuss muscular dystrophy (EDMD), i.e. autosomal-dominant laminopathy (AD-EDMD) and Xlinked emerynopathy (X-EDMD). A set of some matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in serum of EDMD patients and healthy subjects were treated as features. In concluding MMPs and TIMPs levels are helpful to identifying the EDMD patients and the disease progress.