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EN
The fatigue problem induced by wave loads and floater movements of dynamic umbilicals in deepwater is studied. The prediction method of the fatigue life is investigated by considering no-linear local stress due to contact and friction between components of the umbilical. A case study of a dynamic umbilical for 1500 meters depth in South China Sea was presented. The results showed that the more accurate result of the fatigue life was calculated by considering non-linear local stress. The fatigue life by considering local stress with the no-slip assumption was conservative. An obviously longer fatigue life was obtained by considering local stress with the full-slip assumption.
EN
Eutectoid growth, as the important reaction mechanism of the carbon steel heat treatment, is the basis to control the microstructure and performance. At present, most studies have focused on lamellar growth, and did not consider the nucleation process. Mainly due to the nucleation theory is inconclusive, a lot of research can support their own theory in a certain range. Based on the existing nucleation theory, this paper proposes a cooperative nucleation model to simulate the nucleation process of eutectoid growth. In order to ensure that the nucleation process is more suitable to the theoretical results, different correction methods were used to amend the model respectively. The results of numerical simulation show that when the model is unmodified, the lateral growth of single phase is faster than that of longitudinal growth, so the morphology is oval. Then, the effects of diffusion correction, mobility correction and ledges nucleation mechanism correction on the morphology of nucleation and the nucleation rate were studied respectively. It was found that the introduction of boundary diffusion and the nucleation mechanism of the ledges could lead to a more realistic pearlite.
EN
The main work of this paper focuses on the simulation of binary alloy solidification using the phase field model and adaptive octree grids. Ni-Cu binary alloy is used as an example in this paper to do research on the numerical simulation of isothermal solidification of binary alloy. Firstly, the WBM model, numerical issues and adaptive octree grids have been explained. Secondary, the numerical simulation results of three dimensional morphology of the equiaxed grain and concentration variations are given, taking the efficiency advantage of the adaptive octree grids. The microsegregation of binary alloy has been analysed emphatically. Then, numerical simulation results of the influence of thermo-physical parameters on the growth of the equiaxed grain are also given. At last, a simulation experiment of large scale and long-time has been carried out. It is found that increases of initial temperature and initial concentration will make grain grow along certain directions and adaptive octree grids can effectively be used in simulations of microstructure.
EN
A HPLC-DAD method for simultaneous analysis of five flavonoids (rutin, quercitrin, quercetin, kaempferol, and isorhamnetin) in diabetic rat plasma has been developed and validated. Separation of the five flavonoids was accomplished on a C 18 column (250 mm × 4.6 mm i.d., 5-µm particle) and detection was performed at 350 nm. The best resolution was achieved with a methanol-0.1% formic acid gradient at a flow rate of 1.0 mL min −1 . The correlation coefficients for all the calibration plots ( r > 0.999) showed linearity was good over the range tested. The relative standard deviation of the method was less than 7% and 10% for intra- and inter-day assays, and average recovery was between 77.2 and 99.2%. Sensitivity was high and detection limits were between 0.006 and 0.02 µg mL −1 . The method has been successfully used to determine drug concentrations in diabetic rat plasma samples and the pharmacokinetics of the drugs.
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