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Biodegradable scaffolds for bone defect treatment

Antonowicz Magdalena, Brzezinska Karolina, Walke Witold, Taratuta Anna, Pawlik Mateusz

Acta of Bioengineering and Biomechanics

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2023

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Vol. 25, no. 3

EN

Additive techniques in dog orthopedics has recently emerged as a valuable approach in fabricating individualized implants for receiver-specific needs. The scaffolds made by 3D printing are used to replaces bones damaged by injuries sustained in accidents, tumour resections and defects resulting from disease e.g. osteoporosis. In this way can promote the growth and reconstruction of bone defects structure. These implants should have the right properties to ensure the right conditions for bone fusion. It is also important to determine the time of degradation, which is associated with a significant loss of mechanical properties.

2

Modern methods of surface modification for new-generation titanium alloys

Lisoń-Kubica Julia, Taratuta Anna, Goldsztajn Karolina, Antonowicz Magdalena, Walke Witold, Dyner Aneta, Basiaga Marcin

Acta of Bioengineering and Biomechanics

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2022

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Vol. 24, no. 4

147--158

EN

The constantly growing need for the use of implants in osteotomy is mainly due to the aging population and the need for long-term use of this type of biomaterials. Improving implant materials requires the selection of appropriate functional properties. Currently used titanium (Ti) alloys, such as Ti6Al4V and Ti6Al7Nb, are being replaced by materials with better biocompatibility, such as vanadium(V) or niobium (Nb), allowing for creation of the so-called new generation alloys. These new alloys, with the incorporation of zirconium (Zr), iron, and tantalum, possess Young’s modulus close to that of a bone, which further improves the improves the biomaterial’s. biocompatibility. This article describes the atomic layer deposition (ALD) method and its possible applications in the new generation of titanium alloys for biomedical applications. Also, the exemplary results of tin oxide (SnO2) thin coatings deposited by ALD and physical vapor deposition (PVD) methods are presented. This study aimed to evaluate the physicochemical properties of a Ti13Nb13Zr alloy used for elements in the skeletal system. As the temperature and the number of cycles vary, the results demonstrate that the surface area of the samples changes. The uncoated Ti13Nb13Zr alloy exhibits hydrophilic properties. However, all coated specimens improve in this respect and provide improved clinical results. after the applied modification, the samples have a smaller contact angle, but still remain in the range of 0–90°, which makes it possible to conclude that their nature remains hydrophilic. Coating the specimens decreased the mineralization risk of postoperative complications. As a result, the biomaterials demonstrated improved effectiveness, decreased complication indicators, and improved patient well-being.

3

Modification of the surface of spherical aluminosilicates with graphene oxide

Dubiel Agnieszka, Nakonieczny Damian, Walke Witold, Majewska Justyna, Dzido Grzegorz, Nuckowski Paweł, Matus Krzysztof

Engineering of Biomaterials

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2021

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Vol. 24, no. 163

30

4

Atomic layer deposited ZnO films on stainless steel for biomedical applications

Basiaga Marcin, Walke Witold, Kajzer Wojciech, Sambok-Kiełbowicz Agata, Szewczenko Janusz, Simka Wojciech, Szindler Marek, Ziębowicz Bogusław, Lubenets Vira

Archives of Civil and Mechanical Engineering

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2021

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Vol. 21, no. 1

1--15

EN

The main goal of carried out tests were the impact of physicochemical properties of surface layers on the course of processes taking place on the surface of implants made of metallic biomaterials used in the bone system. As a precursor of ZnO, diethylzinc (DEZ) has been used, which reacted with water enabling the deposition of thin films. The chamber temperature was as follows—T = 200°–300 °C. The number of cycles was 500, 1000, and 1500. In the first stage, pitting corrosion test was carried out. Corrosion resistance has been tested under conditions simulating tissue environment. Moreover, the created layers were tested using electrochemical impedance spectroscopy (EIS). The conducted electrochemical tests showed the beneficial effect of the ZnO layer on the substrate made of 316 LVM steel, as evidenced by the obtained parameters describing the corrosion resistance. Furthermore, tests were performed on mechanical properties (scratch test), surface morphology (SEM and AFM method), and physical properties (wettability and thickness layers) for samples with different surface treatments. The investigations of the surface morphology of the applied ZnO layer using the ALD method showed a tendency to inherit the substrate independently of the used application parameters. On the other hand, the tests of adhesion to the substrate showed that the number of cycles of the application process has a fundamental impact on the adhesion of the applied layer to the substrate. Summarizing tests have clearly shown that the number of cycles and temperature in the case of the ZnO coating is significant and positively influences the increase of electrochemical, mechanical, and physical properties of layers.

5

Electrochemical tests of CoCr alloy made with additive technology

Sambok-Kiełbowicz Agata, Walke Witold, Kajzer Wojciech, Paszenda Zbigniew

Engineering of Biomaterials

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2019

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Vol. 22, no. 153 spec. iss.

91

6

Wpływ przygotowania powierzchni oraz parametrów procesu utleniania anodowego na zwilżalność i odporność korozyjną tytanu CPTI GRADE 2

Krupanik Roksana, Rogowska Patrycja, Sarraj Sara, Walke Witold

Aktualne Problemy Biomechaniki

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2019

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z. 18

5--12

PL

Reakcje zachodzące na granicy implant-tkanka kostna determinują sukces procesu implantacji. Są one ściśle związane z cechami powierzchni biomateriału. Badania wskazują, że implanty stosowane w ortopedii i traumatologii powinny się wyróżniać właściwościami osteokonduktywnymi. Według doniesień literaturowych ma na to wpływ odpowiednia chropowatość i zwilżalność powierzchni. Stąd też celem pracy było określenie zależności pomiędzy chropowatością i zwilżalnością powierzchni wytworzonych warstw oraz wartością napięcia prądu (40 – 85V) w procesie ich kształtowania.

EN

Reactions occurring on the implant-bone tissue border determine the success of the implantation process. They are closely related to the surface characteristics of the biomaterial. Research indicates that implants used in orthopedics and traumatology should be distinguished by osteoconductive properties. According to literature reports, it is affected by the appropriate surface roughness and wettability. Therefore, the purpose of the work was to determine the relationship between the roughness and wettability of the surface of the produced layers and the value of current voltage (40 – 85V) in the process of shaping them.