On the noise attenuation in DNA microarray images

• Autorzy: Smolka B. , Szczepański M. , Wojciechowski K. , Plataniotis K. N.
• Języki publikacji: EN

Abstrakty

EN

In this paper a novel method of noise reduction in color images is presented. The new technique is capable of attenuating both impulsive and Gaussian noise, while preserving and even enhancing sharpness of the image edges. Extensive simulations reveal that the new method outperforms significantly the standard techniques widely used in multivariate signal processing. In this work we apply the new noise reduction method for the enhancement of the images of gene chips. We demonstrate that the new technique is capable of reducing various kinds of noise present in microarray images and that it enables efficient spot location and estimation of the gene expression level due to the smoothing effect and preservation of the spot edges. This paper contains the comparison of the new technique of noise reduction with the standard procedures used for the processing of vector valued images, as well as examples of the efficiency of the new algorithm when applied to typical microarray images.

Słowa kluczowe

EN

DNA microarray; gene chips; color image processing; multichannel filters; noise reduction; image enhancement

PL

mikromacierz DNA; przetwarzanie obrazu kolorowego; filtry wielokanałowe; redukcja szumów; wzmocnienie obrazu

• Wydawca: University of Silesia, Institute of Informatics, Computer Systems Department
• Czasopismo: Journal of Medical Informatics & Technologies
• Rocznik: 2001
• Tom: Vol. 2, Part. 1
• Strony: MI19--MI27
• Opis fizyczny: Bibliogr. 16 poz., rys., tab., wykr.

Twórcy

autor

Smolka B.

• Silesian University of Technology, Department of Automatic Control, Akademicka 16 Str, 44-101 Gliwice, Poland

autor

Szczepański M.

• Silesian University of Technology, Department of Automatic Control, Akademicka 16 Str, 44-101 Gliwice, Poland

autor

Wojciechowski K.

• Silesian University of Technology, Department of Automatic Control, Akademicka 16 Str, 44-101 Gliwice, Poland

autor

Plataniotis K. N.

• Edward S. Rogers Sr. Department of Electrical and Computer Engineering, University of Toronto,10 King's College Road, Toronto, Canada,

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