Polyethylene Oxide and their Antibacterial Effects Against some Pathogenic Bacteria

• Autorzy: Abbas Abtisam Jasim , Al-Alaq Farah Tareq , Abdulazee Lubna , Naje Ahmed Samir

Identyfikatory

DOI

10.12912/27197050/152139

• Języki publikacji: EN

Abstrakty

EN

Poly ethylene oxide is an uncrosslinked, non-ionic linear hydrophilic polymer with a variety of molecular weights. PEO is used to make it, and it offers a number of beneficial qualities for medication delivery and antibacterial uses. The antibacterial activity of polyethylene oxide (PEO) at various concentrations as (80, 40, 20, 10 g/ml) against bacteria in Gram-positive Staphylococcus aureus, Streptococcus pyogenes and Lactobacillus sp. and Gram-negative Enterobacter bugandensis, E. coli, Pseudomonas aeruginosa and Klebsiella pneumonia was investigated in this study. The disk diffusion experiment was used to assess the antimicrobial activity of PEO, as well as each isolate’s minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). PEO is shown to have strong broad-spectrum antibacterial action against the bacteria studied, that inhibition zone increase their width inversely proportional to PEO concentration, and has even outpaced the efficacy of certain medicines. PEO had MICs ranging from 10 to 20 g/ml, as well as MBCs of 20 to 80 g/ml. In additional studies, PEO was discovered to be strongly associated with the cell of bacteria, which contributed to its inhibitory impact on bacterial invasion and growth. PEO at an appropriate dose effectively decreased bacterial growth. PEO is highly recommended as a cost-effective antibacterial treatment, Specifically, ectopic infection treatment without the risk of bacterial strains becoming antibiotic-resistant.

Słowa kluczowe

EN

polyethylene oxide; minimum inhibitory concentration; antibacterial activity

• Wydawca: Lubelski Oddział Polskiego Towarzystwo Inżynierii Ekologicznej ; Lublin University of Technology ; WNGB Wydawnictwo Naukowe
• Czasopismo: Ecological Engineering & Environmental Technology
• Rocznik: 2022
• Tom: Vol. 23, iss. 6
• Strony: 26--31
• Opis fizyczny: Bibliogr. 23 poz., rys., tab.

Twórcy

autor

Abbas Abtisam Jasim

• College of Science, AL-Qadisiyah University, Al Diwaniyah, Qadisiyyah Province, Iraq

autor

Al-Alaq Farah Tareq

• Department of Biology, College of Science, University of Babylon, Babylon, Iraq

autor

Abdulazee Lubna

• DNA Research Center, Babylon University, Babylon, Iraq

autor

Naje Ahmed Samir

• Collage of Water Resource Engineering, AL-Qasim Green University, Babylon, 51031, Iraq

• https://orcid.org/0000-0001-8997-4087

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Uwagi

Opracowanie rekordu ze środków MEiN, umowa nr SONP/SP/546092/2022 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2022-2023).