Application of quantum entanglement induced polarization for dual-positron and prompt gamma imaging

• Autorzy: Romanchek Gregory , Shoop Greyson , Abbaszadeh Shiva

Identyfikatory

DOI

10.5604/01.3001.0054.1817

• Języki publikacji: EN

Abstrakty

EN

The intrinsic resolution of Positron Emission Tomography (PET) imaging is bound by positron range effects, wherein the radioactive decay of the imaging tracer occurs at a disjoint location from positron annihilation. Compounding this issue are the variable ranges positrons achieve, depending on tracer species (the energy they are emitted with) and the medium they travel in (bone vs soft tissue, for example) - causing the range to span more than an order of magnitude across various study scenarios (~0.19 mm to ~6.4 mm). Radioisotopes, such as Zr-89, exhibit dual emissions of positron and prompt gammas, offering an opportunity for accurate tracer positioning as prompt gammas originate from the tracer location. These multi-emission radiotracers have historically suffered from increased noise corresponding to the third gamma interfering in annihilation gamma coincidence pairing. Recent advancements, however, have brought to light the unique property of annihilation gammas having scattering kinematics distinct from random gamma pairs. These properties are born from the singular quantum entanglement state available to the gamma pair following para-positronium decay which prescribes linearly orthogonal polarization. Such coherent polarization is not shared by prompt gamma emissions, offering an opportunity for their discrimination. We present an investigation into this technique, comparing the distribution of relevant scattering kinematics of entangled annihilation gammas and corresponding prompt gammas via a Monte Carlo simulation.

Słowa kluczowe

EN

PET imaging; prompt gammas; quantum entanglement; noise reduction; background reduction

• Wydawca: Uniwersytet Jagielloński - Collegium Medicum ; Index Copernicus Sp. z o.o.
• Czasopismo: Bio-Algorithms and Med-Systems
• Rocznik: 2023
• Tom: Vol. 19, no. 1
• Strony: 9--16
• Opis fizyczny: Bibliogr. 11 poz., rys.

Twórcy

autor

Romanchek Gregory

• Department of Nuclear, Plasma, and Radiological Engineering, University of Illinois Urbana-Champaign, Urbana, USA

autor

Shoop Greyson

• Department of Electrical and Computer Engineering, University of California at Santa Cruz, Santa Cruz, USA

autor

Abbaszadeh Shiva

• Department of Electrical and Computer Engineering, University of California at Santa Cruz, Santa Cruz, USA

• https://orcid.org/0000-0001-6345-2408

Bibliografia

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• 9. Enlow E, Diba M, Clayton J, Harris B, Abbaszadeh S. Impact of Flexible Circuit Bonding and System Integration on Energy Resolution of Cross-strip CZT Detectors. IEEE Trans. Radiat. Plasma Med. Sci. 2023;7(6): 580-6.
• 10. Yuli W, Herbst R, Abbaszadeh S. Development and characterization of modular readout design for two-panel head-and-neck dedicated PET system based on CZT detectors. IEEE Trans. Radiat. Plasma Med. Sci. 2021;6(5):517-21.
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Uwagi

Opracowanie rekordu ze środków MEiN, umowa nr SONP/SP/546092/2022 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2022-2023).