Simple and Efficient Three Component One-pot Synthesis of Pyrazolo[1,5,a]pyrimidines

• Autorzy: Morabia A. R. , Naliapara Y. T.

Identyfikatory

DOI

10.18052/www.scipress.com/ILCPA.41.73

• Języki publikacji: EN

Abstrakty

EN

A series of novel 5-(2-bromophenyl)-N-cyclohexyl-2-(methylthio)-6-nitro-7-phenyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carboxamides were synthesized by a one-pot reaction of 5-amino-N-cyclohexyl-3-(methylthio)-1H-pyrazole-4-carboxamide, 1-(2-bromophenyl)-2-nitroethanone and aryl aldehydes in the presence of boric acid in water at refluxing temperature. Structures of compounds were demonstrated by Fourier transform infrared, ¹H NMR, ¹³C NMR and elemental analysis. The advantages of this method are mild reaction condition, good yields, and operational simplicity.

Słowa kluczowe

EN

Pyrazolopyrimidine; 5-amino-N-cyclohexyl-3-(methylthio)-1H-pyrazole-4-carboxamide; 1-(2-bromophenyl)-2-nitroethanone; mild reaction condition

• Wydawca: Przedsiębiorstwo Wydawnictw Naukowych "DARWIN"
• Czasopismo: International Letters of Chemistry, Physics and Astronomy
• Rocznik: 2015
• Tom: Vol. 41
• Strony: 73--81
• Opis fizyczny: Bibliogr. 12 poz., rys., tab., wz.

Twórcy

autor

Morabia A. R.

• Department of Chemistry, Singhania University, Jhunjhunu - 333515, Rajsthan, India

autor

Naliapara Y. T.

• Department of Chemistry, Singhania University, Jhunjhunu - 333515, Rajsthan, India

Bibliografia

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