An observer-based adaptive fuzzy control for prescribing drug dosage in cancer treatment

• Autorzy: Bandpey Razieh Firouzpour , Kalat Ali Akbarzadeh

Identyfikatory

DOI

10.1016/j.bbe.2022.09.004

• Języki publikacji: EN

Abstrakty

EN

In this study, an observer-based adaptive fuzzy controller for prescribing drug dosage in cancer treatment is presented. In the controller design, it is supposed that only the tumor cells and the concentration of Interleukin-2 (IL-2) are measurable. After defining new state variables for the system, a state observer is employed to estimate the unmeasurable state when the unknown dynamic functions of the system are approximated by the fuzzy systems. The stability of the closed-loop system is demonstrated using the Lyapunov theory. Simulation results show the good performance of the observer-based controller taking into account the unknown system dynamics.

Słowa kluczowe

EN

immunotherapy system; cancer drug dosage; adaptive fuzzy control; state observer; Lyapunov stability theory

PL

system immunoterapii; dawkowanie leku; adaptacyjne sterowanie rozmyte; obserwator stanu; teoria stabilności Lapunowa

• Wydawca: Nałęcz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences ; Elsevier
• Czasopismo: Biocybernetics and Biomedical Engineering
• Rocznik: 2022
• Tom: Vol. 42, no. 4
• Strony: 1137--1148
• Opis fizyczny: Bibliogr. 37 poz., rys., tab., wykr.

Twórcy

autor

Bandpey Razieh Firouzpour

• Faculty of Electrical Engineering, Shahrood University of Technology, Shahrood, Iran

autor

Kalat Ali Akbarzadeh

• Faculty of Electrical Engineering, Shahrood University of Technology, Shahrood, Iran

Bibliografia

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Uwagi

PL

Opracowanie rekordu ze środków MEiN, umowa nr SONP/SP/546092/2022 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2022-2023)