Numerical study on flow topology and hemodynamics in tortuous coronary artery with symmetrical and asymmetrical stenosis

• Autorzy: Song Jianfei , Kouidri Smaine , Bakir Farid

Identyfikatory

DOI

10.1016/j.bbe.2020.12.006

• Języki publikacji: EN

Abstrakty

EN

Tortuosity in coronary artery has been found to be greatly related to the potential sites of stenosis in these last years. Many investigations have been carried out based on the tool of Computational Fluid Dynamics (CFD) mainly focusing on the influences of curved artery in blood flow. Within the limited investigations of coupling between stenosis and tortuosity, the stenosis has been considered to be located at the tortuous segment. However, with recent clinical studies, the case of stenosis occurred at non-tortuous segment before tortuosities has been confirmed which has not been paid enough attention yet. Therefore, the present study aims to investigate the disturbed streamlines and hemodynamics in curved and spiral artery considering symmetrical and asymmetrical stenosis upstream these tortuosities. Different stenosis severities, pulse rates and distances between stenosis and tortuosity as controlling parameters have been studied. The distribution of time averaged wall shear stress (TAWSS) and streamlines through tortuous segment have been displayed in order to determine the potential disease sites. Artery surface of TAWSS below critical value has been quantified as well to evaluate the risks of atherosclerosis. The results reveal that larger artery surface of TAWSS below critical value generally goes with smaller pulse rate, larger stenosis severity and distance between stenosis and tortuosity both for curved and spiral artery. However, exceptions were found in the cases of distance of 6 mm in curved artery with symmetrical stenosis and stenosis severity of 50% in spiral artery. Moreover, the spiral tortuosity tends to suppress the potential risks of atherosclerosis compared to curved tortuosity.

Słowa kluczowe

EN

tortuous coronary artery; wall shear stress; hemodynamics; flow topology; computational fluid dynamics

PL

tętnica wieńcowa; naprężenie styczne ścian; hemodynamika; obliczeniowa dynamika płynów

• Wydawca: Nałęcz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences ; Elsevier
• Czasopismo: Biocybernetics and Biomedical Engineering
• Rocznik: 2021
• Tom: Vol. 41, no. 1
• Strony: 142--155
• Opis fizyczny: Bibliogr. 43 poz., rys., wykr.

Twórcy

autor

Song Jianfei

• LIFSE, Arts et Métiers, 151 Boulevard de l'Hopital, Paris, France; LIMSI, CNRS, Université Paris-Saclay, Orsay Cedex, France; Tianjin Key Laboratory of Refrigeration Technology, Tianjin University of Commerce, Tianjin, China

autor

Kouidri Smaine

• LIFSE, Arts et Métiers, 151 Boulevard de l'Hopital, 75013 Paris, France; LIMSI, CNRS, Université Paris-Saclay, Orsay Cedex, France

autor

Bakir Farid

• LIFSE, Arts et Métiers, 151 Boulevard de l'Hopital, Paris, France

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Uwagi

Opracowanie rekordu ze środków MNiSW, umowa Nr 461252 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2021).