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Determination of kinetic parameters of decomposition of tetrahydropyrimidine derivatives

Treść / Zawartość
Identyfikatory
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Some new tetrahydropyrimidine derivatives have been synthesized and their structural determination was done by IR, NMR and mass spectral data. Thermal analysis of these synthesized dihydropyrimidinthiones has been carried out by TGA and DSC techniques. From the thermograms, various kinetic parameters such as order of degradation (n), energy of activation (E), frequency factor (A) and entropy change (ΔS) have been evaluated. Further, thermal stability of tetrahydropyrimidine have been determined which is found to depend on the type of substituent present in the compounds.
Słowa kluczowe
Rocznik
Tom
Strony
23--32
Opis fizyczny
Bibliogr. 20 poz., rys., wz.
Twórcy
autor
  • Department of Chemistry, Saurashtra University, Rajkot-360 005, Gujarat, India
autor
  • Department of Chemistry, Saurashtra University, Rajkot-360 005, Gujarat, India
autor
  • Department of Chemistry, Saurashtra University, Rajkot-360 005, Gujarat, India
Bibliografia
  • 1. Mashkovskii, D.; Medicinals [in Russian], 12th ed., Meditsina, Moscow 1993, Part 1, p. 736; 1993, Part 2, p. 688.
  • 2. Nikolaeva, B.; (ed.), Medicinal Products from Foreign Firms in Russia [in Russian], Astrafarmservis, Moscow, (1993), p. 720.
  • 3. Bahekar, S.; Shinde, D.; Bioorganic and Medicinal Chemistry Letters 14(7) (2004) 1733-1736.
  • 4. Mokale, S.; Shinde, S.; Elgire, R.; Sangshetti, J. and Shinde, D.; Bioorganic and Medicinal Chemistry Letters 20(15) (2010) 4424-4426.
  • 5. Tozkoparan, B.; Ertan, M.; Kelicen, P., Demirdamar, R.; Farmaco. 54(9) (1999) 588-593.
  • 6. Arora, N.; Pandeya, S.; International Journal of Pharmaceutical Sciences and Research 11(1) (2011) 48-52.
  • 7. Linsheng, L.; Guibao, Z.; Chuanlin, Y.; Qun, Z. and Nana, C.; Faming Zhuanli Shenqing (2011), CN 102228461 A 20111102
  • 8. Li, Baoqiu; Li, Lingzi; Ji, Gao.; Faming Zhuanli Shenqing (2011), CN 102274238 A 20111214.
  • 9. Ji-Xin, Y.; Xiao-Qing, C.; Di-Mei, C., and Mao-Lin, H.; Chinese Journal of Chemistry 25(3) (2007) 417-421.
  • 10. Weinhardt, K.; Wallach, M.B.; and Marx, M.; Journal of Medicinal Chemistry 28(6) (1985) 694-698.
  • 11. Champaneri, H.R.; Modi, S.R.; and Naik, H.B.; Asian Journal of Chemistry 6(3) (1994) 737-738.
  • 12. Satyavathi, K.; Naga Ravi, K.T.; Bhoja, R.P. and Sharmila, M.; Asian Journal of Chemistry 22(7) (2010) 5182-5186.
  • 13. Basavaraja, H. S.; Basavaraj, P.; Vijaykumar, M.; Hussain, M. M. and Chidananda, B. N.; Indian journal of heterocylic 20(3) (2011) 237-240.
  • 14. D. Giron, Journal of pharmaceutical and biomedical analysis 4(6) (1986) 755-770.
  • 15. D. Giron, “Thermal Analysis of Drugs and Drug Products” Encyclopedia of Pharmaceutical Technology, Third Edition, (2006).
  • 16. Hardy, M. J.; Charsley E. L. and Warrington, S. B.; Thermal analysis-techniques and applications, The Royal Society of Chemistry, Cambridge (1992), 180-197.
  • 17. Rubinstein M. H.; “Pharmaceutical technology: drug stability.” Chichester: Ellis Horwood; (1989).
  • 18. Brittain H G.; “Physical characterization of pharmaceutical solids.” New York: Marcel Dekker, Inc.; (1995).
  • 19. Freeman, E.S. and Carroll, B.; Journal of physical chemistry 62 (1958) 394-397.
  • 20. Mishra, A.P.; Tiwari, V.; Singhal, R. and Gautam, S.K.; Indian Journal of Chemistry. 41A(10) (2002) 2092-2095.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-f0ad0ee2-3ce7-4736-9aa4-91e6dff67e5c
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