Exosome-hydrogels loaded with metal-organic framework improve skin aging by inhibiting oxidative stress

• Autorzy: Li Li-Jie , Han Qing-Ling , Feng Wen-Jie , Wang Zhan-Peng , Li Hong-Hua

Identyfikatory

DOI

10.2478/pjct-2024-0017

• Języki publikacji: EN

Abstrakty

EN

Solvothermal reactions of Ba(NO₃)₂ with 1,3,5-benzenetricarboxylic acid gave rise to a new coordination polymer of [Ba₆(BTC)₄(H₂O)₉]}n (1 H₃BTC = benzenetricarboxylic acid). The complex 1 was characterized soundly by Fourier transform infrared (FT-IR) spectroscopy, elemental analysis (EA), single-crystal X-ray diffraction (SCXRD), and thermogravimetric analysis (TGA). The framework of 1 has high thermal stability and shows intense luminescence at room temperature. Hyaluronic acid (HA) and carboxymethyl chitosan (CMCS) have good biocompatibility, based on the chemical synthesis method, the HA/CMCS hydrogel was prepared. With exosomes as drug models, we further synthesized novel exosome-loaded metal gel particles and evaluated their effects on oxidative stress in human dermal fibroblasts.

Słowa kluczowe

EN

Ba(II) compound; luminescence; hydrogels; exosome; skin aging

• Wydawca: West Pomeranian University of Technology. Publishing House
• Czasopismo: Polish Journal of Chemical Technology
• Rocznik: 2024
• Tom: Vol. 26, nr 2
• Strony: 42--47
• Opis fizyczny: Bibliogr. 27 poz., rys., tab., wz.

Twórcy

autor

Li Li-Jie

• Plastic Surgery Department of Medical Beauty Center, The First Dongguan Affi liated Hospital of Guangdong Medical University, Dongguan, Guangdong, China

autor

Han Qing-Ling

• Plastic Surgery Department of Medical Beauty Center, The First Dongguan Affi liated Hospital of Guangdong Medical University, Dongguan, Guangdong, China

autor

Feng Wen-Jie

• Plastic Surgery Department of Medical Beauty Center, The First Dongguan Affi liated Hospital of Guangdong Medical University, Dongguan, Guangdong, China

autor

Wang Zhan-Peng

• Plastic Surgery Department of Medical Beauty Center, The First Dongguan Affi liated Hospital of Guangdong Medical University, Dongguan, Guangdong, China

autor

Li Hong-Hua

• Plastic Surgery Department of Medical Beauty Center, The First Dongguan Affi liated Hospital of Guangdong Medical University, Dongguan, Guangdong, China

Bibliografia

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