Synthesis and antimicrobial activity of coumarinyl Schiff base derivatives

• Autorzy: Mishra A. , Rathod J. , Namera D. , Thakrar S. , Shah A.
• Języki publikacji: EN

Abstrakty

EN

We have reported some novel N’-[(1)-ethylidene]-2-(6-methyl-2-oxo-2H-chromen-4-yl) acetohydrazide synthesized by conventional method. The reaction of 2-(6-methyl-2-oxo-2H-chromen-4-yl)acetohydrazide with substituted benzaldehyde in methanol as a solvent yielded a series of (7a-l). The structures of all synthesized compounds are well characterized by Mass, FT-IR, 1H NMR, 13C NMR and elemental analysis. Moreover, all synthesized compounds were screened for in vitro antimicrobial activity against the gram positive (Staphylococcus aureus, Bacilluas subtilis) and gram negative (Escherichia coli, P. aeruginosa, K. pneunonae, Enterobacter) bacterial strain. In which some the compounds show potential inhibition against the test organisms.

Słowa kluczowe

EN

gram positive bacterial; gram negative bacterial; derivatives of coumarin

• Wydawca: Przedsiębiorstwo Wydawnictw Naukowych "DARWIN"
• Czasopismo: International Letters of Chemistry, Physics and Astronomy
• Rocznik: 2014
• Tom: Vol. 11, iss. 3
• Strony: 193--201
• Opis fizyczny: Bibliogr. 26 poz., tab., wz.

Twórcy

autor

Mishra A.

• Chemical Research Laboratory, Department of Chemistry, Saurashtra University, Rajkot - 360005, India

autor

Rathod J.

• Chemical Research Laboratory, Department of Chemistry, Saurashtra University, Rajkot - 360005, India

autor

Namera D.

• Chemical Research Laboratory, Department of Chemistry, Saurashtra University, Rajkot - 360005, India

autor

Thakrar S.

• Chemical Research Laboratory, Department of Chemistry, Saurashtra University, Rajkot - 360005, India

autor

Shah A.

• Chemical Research Laboratory, Department of Chemistry, Saurashtra University, Rajkot - 360005, India

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