HDPE/hydroxyapatite/zeolite composite – characterization and in vitro cytotoxicity

• Autorzy: Appusamy Anandha Moorthy , Lakshmanan Senthil Kumar Kallippatti , Chinnappan Balaji Ayyanar , Subramaniyan Madheswaran

Identyfikatory

DOI

10.14314/polimery.2024.9.4

Warianty tytułu

PL

Kompozyt HDPE/hydroksyapatyt/zeolit – charakterystyka i cytotoksyczność in vitro

• Języki publikacji: EN

Abstrakty

EN

The HDPE/HA/zeolite (65/30/5) composite was obtained by injection molding. Hydroxyapatite (HA) was synthetized using microwave technique. FT-IR showed the presence of hydroxyl and phosphate functional groups. The structure was studied using X-ray diffraction (XRD), and field emission scanning electron microscope (FESEM). The energy dispersive X-ray analysis (EDAX) revealed the presence of O, Ca, P, C, Na, Cl, and Mg. The composite showed improved tensile strength, compressive strength and hardness compared to pure HDPE. In vitro cytotoxicity studies were conducted using L929 cells line. The tests showed 94% viability and 6% toxicity of cells.

PL

Metodą formowania wtryskowego otrzymano kompozyt HDPE/HA/zeolit (65/30/5). Hydroksyapatyt (HA) otrzymano techniką mikrofalową. Badania FT-IR wykazały obecność grup funkcyjnych hydroksylowych i fosforanowych. Strukturę badano za pomocą dyfrakcji rentgenowskiej (XRD) i skaningowego mikroskopu elektronowego z emisją polową (FESEM). Analiza rentgenowska z dyspersją energii (EDAX) wykazała obecność O, Ca, P, C, Na, Cl i Mg. Kompozyt wykazał większą wytrzymałość na rozciąganie, wytrzymałość na ściskanie i twardość w porównaniu z czystym HDPE. Badania cytotoksyczności in vitro przeprowadzono przy użyciu linii komórkowej L929. Testy wykazały 94% żywotności i 6% toksyczności komórek.

Słowa kluczowe

EN

HA; zeolite; HDPE; L929 cells; cytotoxicity

PL

HA; zeolit; HDPE; komórki L929; cytotoksyczność

• Wydawca: Sieć Badawcza Łukasiewicz – Instytut Chemii Przemysłowej
• Czasopismo: Polimery
• Rocznik: 2024
• Tom: Vol. 69, nr 9
• Strony: 500--507
• Opis fizyczny: Bibliogr. 56 poz., tab., rys., wykr.

Twórcy

autor

Appusamy Anandha Moorthy

• Department of Mechanical Engineering, Bannari Amman Institute of Technology, 638401 Erode, India

• https://orcid.org/0000-0001-5540-8941

autor

Lakshmanan Senthil Kumar Kallippatti

• Department of Mechanical Engineering, Bannari Amman Institute of Technology, 638401 Erode, India

• https://orcid.org/0000-0001-8309-0002

autor

Chinnappan Balaji Ayyanar

• Department of Mechanical Engineering, Coimbatore Institute of Technology, Coimbatore, 641014 Tamilnadu, India

• https://orcid.org/0000-0002-2044-4683

autor

Subramaniyan Madheswaran

• Department of Mechanical Engineering, Bannari Amman Institute of Technology, 638401 Erode, India

• https://orcid.org/0000-0001-7106-7104

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Uwagi

Opracowanie rekordu ze środków MNiSW, umowa nr POPUL/SP/0154/2024/02 w ramach programu "Społeczna odpowiedzialność nauki II" - moduł: Popularyzacja nauki (2025).