Simultaneous determination of multiple components in Fuke Yangrong pill by HPLC

• Autorzy: Wang Hua , Zhan Changjuan , Wang Yi

Identyfikatory

DOI

10.1556/1326.2022.01081

• Języki publikacji: EN

Abstrakty

EN

Fuke Yangrong pill, a traditional Chinese patent medicine, with the functions of nourishing qi and blood, soothing liver and relieving depression, regulating menstruation and removing blood stasis, is composed of 16 Chinese medicinal herbs. For quality control purpose, an HPLC method was established for simultaneous quantification of paeoniflorin, hesperidin and ligustilide in Fuke Yangrong pill. With acetonitrile-0.1% formic acid as mobile phase, gradient elution was carried out using Agilent ZORBAX Eclipse Plus C18 column (250 mm × 4.6 mm, 5.0 μm) at 1.0 mL min⁻¹. Detection wavelength was set at 230 nm for paeoniflorin, 280 nm for hesperidin and ligustilide. The temperature was 30 °C. There was a good linearity between the peak area and the concentration of each component to be measured within their linear range (r ≥ 0.9994). The average recoveries were between 98.6% and 102.6% with RSDs no more than 2.93%. This method was validated to be accurate and convenient, which is suitable for the quality control of Fuke Yangrong pill.

Słowa kluczowe

EN

Fuke Yangrong pill; HPLC; paeoniflorin; hesperidin; ligustilide

• Wydawca: University of Silesia in Katowice ; Akademiai Kiado
• Czasopismo: Acta Chromatographica
• Rocznik: 2023
• Tom: Vol. 35, no. 4
• Strony: 326--330
• Opis fizyczny: Bibliogr. 13 poz., rys., tab., wykr.

Twórcy

autor

Wang Hua

• School of Environmental and Pharmaceutical Engineering, Taizhou Institute of Science & Technology, Nanjing University of Science & Technology, Meilan East Road 8#, 225300, Taizhou, China

• https://orcid.org/0000-0002-2614-6281

autor

Zhan Changjuan

• School of Environmental and Pharmaceutical Engineering, Taizhou Institute of Science & Technology, Nanjing University of Science & Technology, Meilan East Road 8#, 225300, Taizhou, China

• https://orcid.org/0000-0002-0925-1629

autor

Wang Yi

• School of Environmental and Pharmaceutical Engineering, Taizhou Institute of Science & Technology, Nanjing University of Science & Technology, Meilan East Road 8#, 225300, Taizhou, China

Bibliografia

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